School of Medicine, Universidad de los Andes, Bogotá, Colombia.
Department of Internal Medicine, Institute of Exercise Medicine and Rehabilitation, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
High Alt Med Biol. 2020 Jun;21(2):135-143. doi: 10.1089/ham.2019.0097. Epub 2020 Feb 18.
To study the criterion validity of three indirect maximal oxygen uptake ([Formula: see text]Omax) assessment equations at altitude. We studied 64 young adults (53% men) at Bogota, Colombia (2600 m altitude). Direct [Formula: see text]Omax was measured by indirect calorimetry using a maximal incremental treadmill protocol. Indirect [Formula: see text]Omax was estimated by two exercise field tests (the 20-m shuttle-run test [20-MST] and the 2-km walking test (UKK)) and one nonexercise method (the perceived functional ability-physical activity rating questionnaire [PFA-PAR]). Altitude-adjusted PFA-PAR was estimated as a 13% linear reduction in PFA-PAR. We calculated Lin concordance coefficients (LCC) and standard error of the estimates (SEEs), and we performed Bland-Altman analyses for each indirect method. Mean [Formula: see text]Omax was 41.2 ± 5.8 mL/kg/min in men and 32.2 ± 3.6 mL/kg/min in women. We found the highest agreement with direct [Formula: see text]Omax for the 20-MST (LCC = 0.79, SEE = 3.91 mL/kg/min), followed in order by the altitude-adjusted PFA-PAR (LCC = 0.71, SEE = 4.12 mL/kg/min), the UKK (LCC = 0.67, SEE = 5.48 mL/kg/min), and the unadjusted PFA-PAR (LCC = 0.57, SEE = 4.75 mL/kg/min). The unadjusted PFA-PAR tended to overestimate [Formula: see text]Omax, but Bland-Altman analysis showed that this bias disappeared after altitude adjustment. Several maximal, submaximal, and nonexercise methods provide estimates of [Formula: see text]Omax with acceptable validity for use in epidemiological studies of populations living at moderate altitude.
研究三种间接最大摄氧量 ([Formula: see text]Omax) 评估方程在高海拔地区的标准效度。我们在哥伦比亚波哥大（海拔 2600 米）研究了 64 名年轻人（53%为男性）。直接 [Formula: see text]Omax 通过间接热量测定法使用最大递增跑步机方案进行测量。间接 [Formula: see text]Omax 通过两种运动测试（20 米穿梭跑测试 [20-MST] 和 2 公里步行测试（UKK））和一种非运动方法（感知功能能力-体力活动评定问卷 [PFA-PAR]）进行估计。海拔调整后的 PFA-PAR 估计为 PFA-PAR 线性降低 13%。我们计算了林一致性系数（LCC）和估计的标准误差（SEEs），并对每种间接方法进行了 Bland-Altman 分析。男性的平均 [Formula: see text]Omax 为 41.2 ± 5.8 mL/kg/min，女性为 32.2 ± 3.6 mL/kg/min。我们发现，20-MST 与直接 [Formula: see text]Omax 的一致性最高（LCC=0.79，SEE=3.91 mL/kg/min），其次是调整后的 PFA-PAR（LCC=0.71，SEE=4.12 mL/kg/min），UKK（LCC=0.67，SEE=5.48 mL/kg/min）和未经调整的 PFA-PAR（LCC=0.57，SEE=4.75 mL/kg/min）。未经调整的 PFA-PAR 倾向于高估 [Formula: see text]Omax，但 Bland-Altman 分析表明，这种偏差在海拔调整后消失。几种最大、次最大和非运动方法可提供 [Formula: see text]Omax 的估计值，在中海拔地区的人群流行病学研究中具有可接受的有效性。
