Kimmel Martin
Dtsch Med Wochenschr. 2020 Feb;145(4):240-247. doi: 10.1055/a-0974-9420. Epub 2020 Feb 18.
Glomerulonephritis, secondary to bacterial, or, more rarely, viral or parasitic infections, is called infection-associated. The epidemiology of infection-associated glomerulonephritis has changed in recent decades. For a long time, the classic form has been acute poststreptococcal glomerulonephritis (APGN), but in developed countries its incidence has declined sharply. However, there is an increase in staphylococcal associated glomerulonephritis (SAGN). The clinical manifestations of APGN and SAGN are different: APGN typically presents with a glomerulonephritis after an infectious latency period (post-infectious), while SAGN typically shows an immune complex glomerulonephritis concomitant with infection (para-infectious). SAGN often presents with an occult infections in older patients with multiple comorbidities.
继发于细菌感染，或更罕见地继发于病毒或寄生虫感染的肾小球肾炎称为感染相关性肾小球肾炎。近几十年来，感染相关性肾小球肾炎的流行病学发生了变化。长期以来，经典形式为急性链球菌感染后肾小球肾炎（APGN），但在发达国家其发病率已大幅下降。然而，葡萄球菌相关性肾小球肾炎（SAGN）的发病率有所上升。APGN和SAGN的临床表现不同：APGN通常在感染潜伏期（感染后）后出现肾小球肾炎，而SAGN通常表现为与感染同时存在的免疫复合物性肾小球肾炎（感染旁）。SAGN在患有多种合并症的老年患者中常表现为隐匿性感染。
