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环状软骨坏死:病例报告及文献综述

Cricoid Chondronecrosis: Case Report and Review of Literature.

作者信息

Mims Mark M, Leclerc Andree A, Smith Libby J

机构信息

University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

University of Montreal, Montreal, QC, Canada.

出版信息

Ann Otol Rhinol Laryngol. 2020 Jul;129(7):662-668. doi: 10.1177/0003489420904974. Epub 2020 Feb 18.

Abstract

OBJECTIVE

Cricoid chondronecrosis is a rare entity that has significant consequences for patients. Reports of its occurrence are scattered in the literature and currently there is no comprehensive review to help guide providers.

METHODS

A case report from our institution is presented. A review of available literature is then provided with assessment of risk factors, signs and symptoms at presentation, laryngeal exam findings, radiologic findings, and surgical techniques.

RESULTS

Twenty-four cases of cricoid chondronecrosis were reviewed from the literature. Patient age ranged from 8 months to 76 years. A history of endotracheal intubation for various reasons was present in all but two cases, and duration of intubation ranged from 6 hours to 28 days. Patients presented with airway compromise in all but two cases-one asymptomatic patient with prior tracheostomy and another with dysphagia after radiation. Dysphonia (n = 6) and dysphagia (n = 3) were less commonly present. Subglottic stenosis (n = 19) was the most common exam finding followed by vocal fold impairment (n = 11). When CT scan findings were reported, fragmentation of the cartilage and/or hypodensity of the central lamina were described in all but one case. Interventions ranged from observation on antibiotics and steroids to surgical therapies including tracheostomy, dilation, and posterior cricoid split, with or without stent placement.

CONCLUSIONS

Cricoid chondronecrosis is a serious, rare entity that can occur even after a short period of endotracheal intubation. Providers must have a high level of suspicion in patients that present with upper airway dyspnea with a history of prior intubation.

LEVEL OF EVIDENCE

Level 4.

摘要

目的

环状软骨坏死是一种罕见疾病,对患者有严重影响。其发病报告在文献中较为分散,目前尚无全面综述来帮助指导临床医生。

方法

本文呈现了我们机构的一例病例报告。随后对现有文献进行综述,评估危险因素、就诊时的体征和症状、喉镜检查结果、影像学检查结果及手术技术。

结果

从文献中回顾了24例环状软骨坏死病例。患者年龄从8个月至76岁不等。除两例外,所有病例均有因各种原因行气管插管史,插管时间从6小时至28天不等。除两例外,所有患者均出现气道受损情况,其中一例为有气管造口术史的无症状患者,另一例为放疗后出现吞咽困难的患者。声音嘶哑(n = 6)和吞咽困难(n = 3)较少见。声门下狭窄(n = 19)是最常见的检查发现,其次是声带受损(n = 11)。当报告CT扫描结果时,除一例病例外,所有病例均描述了软骨碎裂和/或中央板低密度影。干预措施包括使用抗生素和类固醇进行观察,以及手术治疗,如气管造口术、扩张术和后环状软骨劈开术,有无放置支架均可。

结论

环状软骨坏死是一种严重的罕见疾病,即使在短期气管插管后也可能发生。对于有气道呼吸困难且有插管史的患者,临床医生必须高度怀疑此病。

证据级别

4级。

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