• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颈髓损伤后神经病理性疼痛的一种不常见表现:病例报告。

An unusual presentation of neuropathic pain following cervical spinal cord injury: a case report.

机构信息

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea.

Department of Physical Medicine and Rehabilitation, Centre hospitalier de l'Université de Montréal, 3840, Saint-Urbain St., Montreal, QC, H2W 1T8, Canada.

出版信息

BMC Neurol. 2020 Feb 18;20(1):61. doi: 10.1186/s12883-020-01644-0.

DOI:10.1186/s12883-020-01644-0
PMID:32070321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7029607/
Abstract

BACKGROUND

We report a patient with unusual occipital neuropathic pain (at-level neuropathic pain) due to a small central cervical spinal cord injury (SCI).

CASE PRESENTATION

A 50-year-old man presented with severe bilateral occipital pain after falling from a height of 2 m, 2 weeks ago. The degree of pain was evaluated to be 9 out of 10 using the numeric rating scale (NRS). The nature of the pain was tingling, burning, and piercing, and hyperalgesia was present over the bilateral posterior head regions. Greater occipital nerve block with bupivacaine and dexamethasone was not effective. On axial T2-cervical magnetic resonance imaging (MRI), a focal high signal change was observed in the central portion of the spinal cord at the C2 level. We deliberated that the patient's pain was due to the SCI observed on MRI, and after administration of oral medications, the NRS pain score reduced from 9 to 2.

CONCLUSIONS

Neuropathic pain caused by SCI varies according to the location and degree of injury of the pain-related neural tracts; therefore, clinicians should closely observe the pain patterns and findings on imaging in patients with SCI to determine the cause of pain accurately.

摘要

背景

我们报告了一例由于小的中央颈脊髓损伤(SCI)导致的不常见的枕部神经性疼痛(同水平神经性疼痛)的患者。

病例介绍

一名 50 岁男性,2 周前从 2 米高处坠落,出现严重双侧枕部疼痛。疼痛程度用数字评分量表(NRS)评估为 9 分(满分 10 分)。疼痛性质为刺痛、烧灼感和刺痛感,双侧后头部存在痛觉过敏。布比卡因和地塞米松的枕大神经阻滞无效。颈椎轴位 T2 磁共振成像(MRI)显示 C2 水平脊髓中央部分有局灶性高信号改变。我们认为患者的疼痛是由 MRI 观察到的 SCI 引起的,口服药物治疗后,NRS 疼痛评分从 9 分降至 2 分。

结论

SCI 引起的神经性疼痛根据与疼痛相关的神经束的损伤位置和程度而不同;因此,临床医生应密切观察 SCI 患者的疼痛模式和影像学发现,以准确确定疼痛的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a3/7029607/d9ddb116e793/12883_2020_1644_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a3/7029607/d9ddb116e793/12883_2020_1644_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a3/7029607/d9ddb116e793/12883_2020_1644_Fig1_HTML.jpg

相似文献

1
An unusual presentation of neuropathic pain following cervical spinal cord injury: a case report.颈髓损伤后神经病理性疼痛的一种不常见表现:病例报告。
BMC Neurol. 2020 Feb 18;20(1):61. doi: 10.1186/s12883-020-01644-0.
2
Cervical spinal cord injury-induced neuropathic pain in male mice is associated with a persistent pro-inflammatory macrophage/microglial response in the superficial dorsal horn.雄性小鼠脊髓颈段损伤诱导的神经性疼痛与浅背角中持续存在的促炎型巨噬细胞/小胶质细胞反应有关。
Exp Neurol. 2021 Sep;343:113757. doi: 10.1016/j.expneurol.2021.113757. Epub 2021 May 12.
3
Segmental hypersensitivity and spinothalamic function in spinal cord injury pain.脊髓损伤性疼痛中的节段性感觉过敏与脊髓丘脑束功能
Exp Neurol. 2007 Sep;207(1):139-49. doi: 10.1016/j.expneurol.2007.06.001. Epub 2007 Jun 18.
4
GLT1 overexpression reverses established neuropathic pain-related behavior and attenuates chronic dorsal horn neuron activation following cervical spinal cord injury.谷氨酸转运体1(GLT1)过表达可逆转已确立的神经性疼痛相关行为,并减轻颈脊髓损伤后慢性背角神经元的激活。
Glia. 2016 Mar;64(3):396-406. doi: 10.1002/glia.22936. Epub 2015 Oct 23.
5
Administration of ONO-2506 suppresses neuropathic pain after spinal cord injury by inhibition of astrocytic activation.ONO-2506 的给药通过抑制星形胶质细胞的激活来抑制脊髓损伤后的神经性疼痛。
Spine J. 2019 Aug;19(8):1434-1442. doi: 10.1016/j.spinee.2019.04.006. Epub 2019 Apr 8.
6
Long-term physical therapy for neuropathic pain after cervical spinal cord injury and resting state electroencephalography: a case report.颈脊髓损伤后神经病理性疼痛的长期物理治疗及静息态脑电图:病例报告。
Spinal Cord Ser Cases. 2022 Apr 9;8(1):41. doi: 10.1038/s41394-022-00510-0.
7
Characterization of traumatic spinal cord injury model in relation to neuropathic pain in the rat.大鼠创伤性脊髓损伤模型与神经性疼痛的相关性特征分析
Somatosens Mot Res. 2019 Mar;36(1):14-23. doi: 10.1080/08990220.2018.1563537. Epub 2019 Mar 14.
8
Analgesia-enhancing effects of repetitive transcranial magnetic stimulation on neuropathic pain after spinal cord injury:An fNIRS study.重复经颅磁刺激对脊髓损伤后神经性疼痛的镇痛作用:一项近红外光谱研究。
Restor Neurol Neurosci. 2019;37(5):497-507. doi: 10.3233/RNN-190934.
9
Hypothalamic-pituitary-adrenal axis function in traumatic spinal cord injury-related neuropathic pain: a case-control study.创伤性脊髓损伤相关神经性疼痛患者的下丘脑-垂体-肾上腺轴功能:一项病例对照研究。
J Endocrinol Invest. 2019 Aug;42(8):923-930. doi: 10.1007/s40618-019-1002-9. Epub 2019 Jan 9.
10
Intrathecal injection of carbenoxolone, a gap junction decoupler, attenuates the induction of below-level neuropathic pain after spinal cord injury in rats.鞘内注射缝隙连接解偶联剂 carbenoxolone 可减轻大鼠脊髓损伤后下位神经性疼痛的诱导。
Exp Neurol. 2010 Jul;224(1):123-32. doi: 10.1016/j.expneurol.2010.03.002. Epub 2010 Mar 11.

引用本文的文献

1
Effectiveness of Intravenous Immunoglobulin for Management of Neuropathic Pain: A Narrative Review.静脉注射免疫球蛋白治疗神经性疼痛的有效性:一项叙述性综述。
J Pain Res. 2020 Nov 12;13:2879-2884. doi: 10.2147/JPR.S273475. eCollection 2020.

本文引用的文献

1
Neck-to-shoulder pain as an unusual presentation of pulmonary embolism in a patient with cervical spinal cord injury: A case report.颈肩痛作为颈椎脊髓损伤患者肺栓塞的一种不寻常表现:一例病例报告。
Medicine (Baltimore). 2017 Oct;96(42):e8288. doi: 10.1097/MD.0000000000008288.
2
Neuropathic pain.神经性疼痛。
Nat Rev Dis Primers. 2017 Feb 16;3:17002. doi: 10.1038/nrdp.2017.2.
3
Neuropathic pain prevalence following spinal cord injury: A systematic review and meta-analysis.脊髓损伤后神经性疼痛的患病率:一项系统评价与荟萃分析。
Eur J Pain. 2017 Jan;21(1):29-44. doi: 10.1002/ejp.905. Epub 2016 Jun 24.
4
Characteristics of neuropathic pain in patients with spinal cord injury.脊髓损伤患者神经性疼痛的特征
Ann Rehabil Med. 2014 Jun;38(3):327-34. doi: 10.5535/arm.2014.38.3.327. Epub 2014 Jun 26.
5
Central cord syndrome.中央索综合征。
J Am Acad Orthop Surg. 2009 Dec;17(12):756-65. doi: 10.5435/00124635-200912000-00004.
6
Residual spinothalamic tract pathways predict development of central pain after spinal cord injury.脊髓丘脑束残余通路可预测脊髓损伤后中枢性疼痛的发生。
Brain. 2008 Sep;131(Pt 9):2387-400. doi: 10.1093/brain/awn169. Epub 2008 Jul 31.
7
The crossing of the spinothalamic tract.脊髓丘脑束的交叉。
Brain. 2001 Apr;124(Pt 4):793-803. doi: 10.1093/brain/124.4.793.