Commonwealth Scientific and Industrial Research Organization (CSIRO) Health and Biosecurity, GPO Box 2583, Brisbane, QLD 4001, Australia.
Commonwealth Scientific and Industrial Research Organization (CSIRO) Health and Biosecurity, GPO Box 2583, Brisbane, QLD 4001, Australia.
Curr Opin Insect Sci. 2020 Apr;38:6-14. doi: 10.1016/j.cois.2019.12.003. Epub 2020 Jan 30.
With the advent of new genetic technologies such as gene silencing and gene drive, efforts to develop additional management tools for weed management is gaining significant momentum. These technologies promise novel ways to develop sustainable weed control options because gene silencing can switch-off genes mediating adaptation (e.g. growth, herbicide resistance), and gene drive can be used to spread modified traits and to engineer wild populations with reduced fitness. However, applying gene silencing and/or gene drive is expected to be inherently complex as their application is constrained by several methodological and technological difficulties. In this review we explore the challenges of these technologies, and discuss strategies and resources accessible to accelerate the development of gene-tech based tools for weed management. We also highlight how gene technologies can be integrated into existing management tactics such as classical biological control, and their possible interactions.
随着基因沉默和基因驱动等新基因技术的出现，人们正在努力开发更多的杂草管理工具，这方面的工作势头越来越强劲。这些技术有望为可持续的杂草控制提供新的途径，因为基因沉默可以关闭介导适应性的基因（例如生长、抗除草剂），而基因驱动可以用来传播改良的性状，并通过工程设计使野生种群的适应性降低。然而，由于应用这些技术受到若干方法学和技术方面的困难的限制，预计应用基因沉默和/或基因驱动将具有内在的复杂性。在本综述中，我们探讨了这些技术的挑战，并讨论了可用于加速基于基因技术的杂草管理工具的开发的策略和资源。我们还强调了基因技术如何能够被整合到现有的管理策略中，如经典的生物防治，以及它们可能的相互作用。
