Department of Radiology, Ankara University School of Medicine, Ankara, Turkey.
Department of Neurology, Ankara University School of Medicine, Ankara, Turkey.
Diagn Interv Radiol. 2020 May;26(3):249-254. doi: 10.5152/dir.2019.19259.
We aimed to assess the diagnostic performance of transluminal attenuation difference (TAD) in predicting the severity of internal carotid artery (ICA) stenosis.
The study cohort consisted of 48 patients with <50% stenosis, 50%-69% stenosis, 70%-99% stenosis, and 51 controls without plaque development in ICA. A total of 143 measurements were performed through right and left internal and common carotid arteries. The TAD ratio was calculated as the difference between the mean attenuation values of the common carotid artery (CCA) and ICA, divided by the MAV of the CCA, multiplied by 100.
TAD ratio was significantly higher in severe (>70%) stenosis compared with control arteries and low-moderate stenosis. A TAD ratio cutoff of 4.5 predicted 70%-99% stenosis with a sensitivity of 100% and specificity of 93%. The inter- and intraobserver agreements in TAD measurements were almost perfect (ICC, 0.89-0.86).
Assessment of TAD ratio predicts the degree of stenosis in concordance with NASCET system.
我们旨在评估管腔衰减差（TAD）在预测颈内动脉（ICA）狭窄严重程度方面的诊断性能。
研究队列包括 48 例狭窄程度<50%、50%-69%、70%-99%的患者和 51 例无 ICA 斑块形成的对照组。通过右侧和左侧颈内和颈总动脉共进行了 143 次测量。TAD 比值计算为颈总动脉（CCA）和 ICA 的平均衰减值之间的差异，除以 CCA 的平均幅度值，乘以 100。
与对照组和低中度狭窄相比，严重（>70%）狭窄患者的 TAD 比值显著更高。TAD 比值为 4.5 的截断值可预测 70%-99%狭窄，其灵敏度为 100%，特异性为 93%。TAD 测量的观察者间和观察者内一致性几乎为完美（ICC，0.89-0.86）。
TAD 比值评估与 NASCET 系统一致，可预测狭窄程度。
