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AMPK against NASH.

作者信息

Strzyz Paulina

机构信息

Nature Reviews Molecular Cell Biology, .

出版信息

Nat Rev Mol Cell Biol. 2020 Apr;21(4):181. doi: 10.1038/s41580-020-0225-0.

DOI:10.1038/s41580-020-0225-0
PMID:32071435
Abstract
摘要

相似文献

1
AMPK against NASH.腺苷酸活化蛋白激酶对抗非酒精性脂肪性肝炎
Nat Rev Mol Cell Biol. 2020 Apr;21(4):181. doi: 10.1038/s41580-020-0225-0.
2
Many roads lead to Rome: The FGF4-AMP-activated protein kinase-Caspase 6 signal axis in NAFLD and NASH.条条大路通罗马：非酒精性脂肪性肝病和非酒精性脂肪性肝炎中的FGF4-AMP激活蛋白激酶-半胱天冬酶6信号轴
Hepatology. 2022 Oct;76(4):911-913. doi: 10.1002/hep.32454. Epub 2022 Mar 25.
3
Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress.去甲基小檗碱通过激活AMPK和抑制氧化应激减轻非酒精性脂肪性肝病。
Biochem Biophys Res Commun. 2016 Apr 15;472(4):603-9. doi: 10.1016/j.bbrc.2016.03.019. Epub 2016 Mar 9.
4
Hydrogen sulfide reduces serum triglyceride by activating liver autophagy via the AMPK-mTOR pathway.硫化氢通过激活 AMPK-mTOR 通路诱导肝自噬来降低血清三酰甘油。
Am J Physiol Endocrinol Metab. 2015 Dec 1;309(11):E925-35. doi: 10.1152/ajpendo.00294.2015. Epub 2015 Oct 6.
5
Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats.绿茶多酚通过上调高脂喂养的 Zucker 肥胖大鼠的 AMPK 激活来改善非酒精性脂肪性肝病。
World J Gastroenterol. 2017 Jun 7;23(21):3805-3814. doi: 10.3748/wjg.v23.i21.3805.
6
Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity.布舍他汀类似物通过抑制 ATP 合酶活性缓解高脂肪饮食诱导的小鼠非酒精性脂肪肝/非酒精性脂肪性肝炎。
Br J Pharmacol. 2019 Aug;176(16):2877-2893. doi: 10.1111/bph.14713. Epub 2019 Jul 4.
7
Treatment of nonalcoholic fatty liver disease: role of AMPK.非酒精性脂肪性肝病的治疗：AMPK的作用
Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E730-E740. doi: 10.1152/ajpendo.00225.2016. Epub 2016 Aug 30.
8
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.依泽替米贝是一种NPC1L1抑制剂，是一种有效的Nrf2激活剂，可保护小鼠免受饮食诱导的非酒精性脂肪性肝炎。
Free Radic Biol Med. 2016 Oct;99:520-532. doi: 10.1016/j.freeradbiomed.2016.09.009. Epub 2016 Sep 12.
9
Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice.藏红花酸通过激活 db/db 小鼠的 AMPK 信号通路改善肝脂肪变性。
Lipids Health Dis. 2019 Jan 8;18(1):11. doi: 10.1186/s12944-018-0955-6.
10
High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling.高海拔慢性缺氧通过调节线粒体和 AMPK 信号改善肥胖诱导的非酒精性脂肪肝疾病。
Life Sci. 2020 Jul 1;252:117633. doi: 10.1016/j.lfs.2020.117633. Epub 2020 Apr 11.

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Deficiency of β-arrestin2 ameliorates MASLD in mice by promoting the activation of TAK1/AMPK signaling.β-抑制蛋白2的缺乏通过促进TAK1/AMPK信号通路的激活改善小鼠的代谢相关脂肪性肝病。
Arch Pharm Res. 2025 May 8. doi: 10.1007/s12272-025-01544-2.
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Impact of Dapagliflozin on Hepatic Lipid Metabolism and a Dynamic Model of Ketone Body Levels.达格列净对肝脏脂质代谢的影响及酮体水平的动态模型
AAPS J. 2025 Feb 3;27(1):38. doi: 10.1208/s12248-025-01024-x.
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Spirulina platensis Peptide-Loaded Nanoliposomes Alleviate Hepatic Lipid Accumulation in Male Wistar Rats by Influencing Redox Homeostasis and Lipid Metabolism via the AMPK Signaling Pathway.
钝顶螺旋藻肽负载纳米脂质体通过AMPK信号通路影响氧化还原稳态和脂质代谢减轻雄性Wistar大鼠肝脏脂质积累
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Research Progress Regarding the Effect and Mechanism of Dietary Polyphenols in Liver Fibrosis.膳食多酚防治肝纤维化的作用及其机制研究进展。
Molecules. 2023 Dec 25;29(1):127. doi: 10.3390/molecules29010127.
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Cellular heterogeneity and plasticity during NAFLD progression.非酒精性脂肪性肝病进展过程中的细胞异质性和可塑性。
Front Mol Biosci. 2023 Aug 11;10:1221669. doi: 10.3389/fmolb.2023.1221669. eCollection 2023.
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Gluten worsens non-alcoholic fatty liver disease by affecting lipogenesis and fatty acid oxidation in diet-induced obese apolipoprotein E-deficient mice.谷蛋白通过影响饮食诱导肥胖载脂蛋白 E 缺陷小鼠的脂肪生成和脂肪酸氧化而使非酒精性脂肪性肝病恶化。
Mol Cell Biochem. 2024 Jun;479(6):1335-1347. doi: 10.1007/s11010-023-04802-3. Epub 2023 Jul 4.
7
Activation of AMPK Entails the Protective Effect of Royal Jelly against High-Fat-Diet-Induced Hyperglycemia, Hyperlipidemia, and Non-Alcoholic Fatty Liver Disease in Rats.蜂王浆通过激活 AMPK 对高脂饮食诱导的大鼠高血糖、高血脂和非酒精性脂肪肝发挥保护作用。
Nutrients. 2023 Mar 18;15(6):1471. doi: 10.3390/nu15061471.
8
The Emerging Role of Extracellular Vesicles and Autophagy Machinery in NASH-Future Horizons in NASH Management.细胞外囊泡和自噬机制在 NASH 中的新兴作用——NASH 管理的未来展望。
Int J Mol Sci. 2022 Oct 12;23(20):12185. doi: 10.3390/ijms232012185.
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Activated AMP-activated protein kinase prevents hepatic steatosis, oxidative stress and inflammation in primary chicken hepatocytes.活化的AMP活化蛋白激酶可预防原代鸡肝细胞中的肝脂肪变性、氧化应激和炎症。
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Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK.鞣花酸通过激活 AMPK 来防治链脲佐菌素诱导的糖尿病大鼠非酒精性脂肪肝病。
Pharm Biol. 2022 Dec;60(1):25-37. doi: 10.1080/13880209.2021.1990969.