Xu Lin, Zhang Dawei, Ronson Tanya K, Nitschke Jonathan R
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China.
Angew Chem Int Ed Engl. 2020 May 4;59(19):7435-7438. doi: 10.1002/anie.202001059. Epub 2020 Mar 18.
The use of di(2-pyridyl)ketone in subcomponent self-assembly is introduced. When combined with a flexible triamine and zinc bis(trifluoromethanesulfonyl)imide, this ketone formed a new Zn L tetrahedron 1 bearing twelve uncoordinated pyridyl units around its metal-ion vertices. The acid stability of 1 was found to be greater than that of the analogous tetrahedron 2 built from 2-formylpyridine. Intriguingly, the peripheral presence of additional pyridine rings in 1 resulted in distinct guest binding behavior from that of 2, affecting guest scope as well as binding affinities. The different stabilities and guest affinities of capsules 1 and 2 enabled the design of systems whereby different cargoes could be moved between cages using acid and base as chemical stimuli.
介绍了二（2-吡啶基）酮在亚组分自组装中的应用。当与柔性三胺和双（三氟甲磺酰）亚胺锌结合时，这种酮形成了一种新的锌L四面体1，在其金属离子顶点周围带有十二个未配位的吡啶单元。发现1的酸稳定性大于由2-甲酰基吡啶构建的类似四面体2的酸稳定性。有趣的是，1中额外吡啶环的外围存在导致其客体结合行为与2不同，影响了客体范围以及结合亲和力。胶囊1和2的不同稳定性和客体亲和力使得能够设计出这样的系统，即可以使用酸和碱作为化学刺激物在笼子之间转移不同的货物。
