Li T C, Bromham D R
Department of Obstetrics and Gynaecology, St James's University Hospital, Leeds.
Br J Obstet Gynaecol. 1988 Nov;95(11):1152-8. doi: 10.1111/j.1471-0528.1988.tb06793.x.
The perinatal outcome associated with fetomaternal macrotransfusion (FMMT), defined as fetomaternal haemorrhage greater than or equal to 10 ml, was investigated in a study group of 179 cases of FMMT and compared with the outcome in 322 controls selected from the same population. Perinatal mortality and morbidity occurred more frequently in the case group (P less than 0.01). The mean Apgar score at 1 min and the cord haemoglobin level differed significantly between the case and control groups (P less than 0.01) and showed a significant inverse correlation with the estimated volumes of FMMT (P less than 0.0001). There was no significant difference in birthweight between the case and control groups. The mean estimated volumes of FMMT associated with perinatal mortality and with low cord haemoglobin (less than or equal to 9.0 g/dl) were significantly higher than the mean volume in the case group as a whole, which suggests the possibility of adapting these observations to a screening procedure.
对179例母胎大量输血（FMMT，定义为母胎出血量大于或等于10毫升）的研究组进行了与围产期结局相关的调查，并与从同一人群中选取的322例对照组的结局进行了比较。围产期死亡率和发病率在病例组中更频繁出现（P小于0.01）。病例组和对照组之间1分钟时的平均阿氏评分和脐带血红蛋白水平有显著差异（P小于0.01），并且与估计的母胎大量输血血量呈显著负相关（P小于0.0001）。病例组和对照组之间的出生体重没有显著差异。与围产期死亡率和低脐带血红蛋白（小于或等于9.0克/分升）相关的母胎大量输血平均估计血量显著高于整个病例组的平均血量，这表明有可能将这些观察结果应用于筛查程序。
