视盘小凹患者视神经乳头的血管结构
The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen.
作者信息
Vahlgren Julie, Malmqvist Lasse, Rueløkke Lea Lybæk, Karlesand Isabelle, Lindberg Anne-Sofie Wessel, Hamann Steffen
机构信息
Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.
DTU Compute, Technical University of Denmark, Lyngby, Denmark.
出版信息
Neuroophthalmology. 2019 May 28;44(1):5-10. doi: 10.1080/01658107.2019.1613666. eCollection 2020 Feb.
The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case-control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p < 0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p < 0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.
在一项病例对照研究中，目的是使用基于计算机的眼底分析来分析视盘玻璃疣（ODD）患者的视盘血管结构。与对照组相比，ODD组的视网膜中央动脉（CRA）起源明显更集中（p < 0.001）和原发性CRA分支（p = 0.008），CRA分叉数量更多（p = 0.02），垂直视盘直径更大（p = 0.02）以及杯盘比更小（p < 0.001）。两组的CRA起源大多在鼻侧区域内。ODD患者视盘独特的血管结构在理解ODD的致病原因方面可能起作用。
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