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中重度阻塞性睡眠呼吸暂停患者持续十年接受持续气道正压通气治疗。

Ten-year adherence to continuous positive airway pressure treatment in patients with moderate-to-severe obstructive sleep apnea.

机构信息

Department of Otorhinolaryngology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan.

Department of Otorhinolaryngology, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, 105-8461, Japan.

出版信息

Sleep Breath. 2020 Dec;24(4):1565-1571. doi: 10.1007/s11325-020-02033-0. Epub 2020 Feb 19.

Abstract

PURPOSE

This study aimed to evaluate the 10-year adherence to and identify the predictors of dropout from continuous positive airway pressure (CPAP) treatment for patients with moderate-to-severe obstructive sleep apnea (OSA).

METHODS

We retrospectively analyzed the continuity, dropout, or other behaviors of 181 patients who initiated CPAP treatment at the Tokyo Dental College Ichikawa General Hospital from January 2003 to June 2005.

RESULTS

Among a total of 181 patients, 56 (30.9%) dropped out of the treatment. Among the 125 patients who did not dropout, 54 continued CPAP treatment for > 10 years, 16 completed the treatment with OSA improvement, and 7 could not complete the treatment owing to unavoidable reasons such as death, dementia, hospitalization for serious illness, or migration to other countries. Further, 47 patients moved to another facility, whereas 1 patient purchased a CPAP device and stopped visiting our facility. Among the 56 patients who dropped out, approximately 50% of the patients dropped out within a year, and all dropped out within 76 months. Comparing demographics, OSA parameters, and CPAP parameters between the patients who did and did not drop out of the treatment, Cox regression analysis indicated that body mass index (BMI) and the first-month utilization rate were clinical variables that were independently associated with discontinuation of CPAP treatment.

CONCLUSION

The results of this study show that BMI and the first-month utilization rate of CPAP treatment are the predictors of the long-term adherence to this treatment.

摘要

目的

本研究旨在评估中重度阻塞性睡眠呼吸暂停(OSA)患者连续气道正压通气(CPAP)治疗的 10 年依从性,并确定其脱落的预测因素。

方法

我们回顾性分析了 2003 年 1 月至 2005 年 6 月在东京齿科大学市川综合医院开始 CPAP 治疗的 181 例患者的连续性、脱落或其他行为。

结果

在总共 181 例患者中,有 56 例(30.9%)脱落治疗。在未脱落的 125 例患者中,54 例继续 CPAP 治疗>10 年,16 例治疗后 OSA 改善,7 例因死亡、痴呆、因严重疾病住院或移居其他国家等不可避免的原因无法完成治疗。此外,47 例患者转至其他机构,1 例患者购买 CPAP 设备并停止到我院就诊。在 56 例脱落的患者中,约 50%的患者在一年内脱落,所有患者在 76 个月内脱落。比较治疗脱落和未脱落患者的人口统计学、OSA 参数和 CPAP 参数,Cox 回归分析表明,体重指数(BMI)和第一个月的使用率是与 CPAP 治疗中断相关的独立临床变量。

结论

本研究结果表明,BMI 和 CPAP 治疗的第一个月使用率是该治疗长期依从性的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062b/7679333/eb88345d2672/11325_2020_2033_Fig1_HTML.jpg

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