Westcott Sarah K, Wung William, Glassy Matthew, Singh Gagan D, Smith Thomas W, Fan Dali, Rogers Jason H
Division of Cardiovascular Medicine, University of California Davis Medical Center, Sacramento, California.
Catheter Cardiovasc Interv. 2020 Sep 1;96(3):E387-E392. doi: 10.1002/ccd.28796. Epub 2020 Feb 20.
To propose a novel method for mapping leak location and frequency to a clock-face representation of the left atrial appendage (LAA) ostium.
LAA occlusion with the Watchman device (WD) is an established therapy to reduce thromboembolic events in patients with atrial fibrillation (AF) and intolerance to long-term oral anticoagulation. Postimplantation leaks are known sequelae, but leak locations and characteristics are poorly described.
We retrospectively reviewed 101 consecutive WD implants from April 2015 to February 2018. Leak locations from 6-week post-implant transesophageal echocardiograms were mapped to a clock-face representation of the LAA ostium: 12:00 as cranial near the limbus, 3:00 as anterior toward the pulmonary artery, 6:00 as caudal near the mitral annulus, and 9:00 as posterior. Patient demographics, LAA dimensions, and procedural characteristics were also collected.
Thirty-four patients had ≥1 leak totaling 45 leaks at 6-week follow-up. Baseline patient demographics showed a mean age 77, CHA DS VASc 4.69, and 64% of patients with permanent AF. No patient had a detectable leak at the time of implant. At 6 weeks, mean leak size was 2.67 ± 0.89 mm with no leak over 5 mm (largest 4.60 mm). Most leaks occurred along the posterior 6:00-12:00 segment (39/45) and the 6:00-9:00 quadrant (16/45).
Six-week post-WD implant leaks localize to the posterior LAA ostium. This could result from the elliptical LAA orifice, differential LAA tissue composition, or implantation technique. This study provides a novel method for describing the location of post-implant leaks and serves as the basis for further investigations.
提出一种将左心耳(LAA)开口处漏血位置和频率映射到钟面表示法的新方法。
使用Watchman装置(WD)进行LAA封堵是一种已确立的治疗方法,用于减少房颤(AF)且不耐受长期口服抗凝治疗的患者发生血栓栓塞事件。植入后漏血是已知的后遗症,但漏血位置和特征描述甚少。
我们回顾性分析了2015年4月至2018年2月连续101例WD植入病例。将植入后6周经食管超声心动图检查的漏血位置映射到LAA开口处的钟面表示法:12:00为靠近边缘的头侧,3:00为朝向肺动脉的前侧,6:00为靠近二尖瓣环的尾侧,9:00为后侧。还收集了患者人口统计学资料、LAA尺寸和手术特征。
34例患者在6周随访时有≥1处漏血,共45处漏血。基线患者人口统计学资料显示平均年龄77岁,CHA₂DS₂-VASc评分为4.69,64%为永久性AF患者。植入时无患者有可检测到的漏血。在6周时,平均漏血大小为2.67±0.89mm,无漏血超过5mm(最大4.60mm)。大多数漏血发生在6:00-12:00后侧段(39/45)和6:00-9:00象限(16/45)。
WD植入后6周漏血定位于LAA开口处后侧。这可能是由于LAA口呈椭圆形、LAA组织成分不同或植入技术所致。本研究提供了一种描述植入后漏血位置的新方法,并为进一步研究奠定了基础。