Pollock Frederic H, Maurer J P, Sop Aaron, Callegai Jonathan, Broce Mike, Kali Maher, Spindel Jeffrey F
Orthopedics. 2020 May 1;43(3):168-172. doi: 10.3928/01477447-20200213-03. Epub 2020 Feb 20.
Nonoperative treatment has become the standard of care for the majority of humeral shaft fractures. Published studies have mainly come from trauma centers with a young cohort of patients. The purpose of this study was to determine the nonunion rate of humeral shaft fractures in patients older than 55 years. A retrospective study was performed on a group of orthopedic trauma group treated at a level I trauma center during a 10-year period (2007-2017). Patients 55 years or older and treated for a humeral shaft fracture nonoperatively, with or without manipulation, were identified. Nonunion was defined by no bridging callus radiographically or by gross motion at the fracture at least 12 weeks from injury. There were 31 patients identified with humeral shaft fractures who met the inclusion criteria. The cohort included 21 (67.7%) females and 10 (32.3%) males with a mean age of 72.5 years (range, 55-92 years). Twenty-one fractures went on to union, and there were 10 nonunions, with no significant differences in the demographics or comorbidities. There was no correlation between AO/OTA fracture classification or fracture location and union status. There was a tendency toward higher risk of nonunion in proximal third humeral shaft fractures (45%) compared with middle (26%) and distal third (20%) humeral shaft fractures, although this was not statistically significant. The overall nonunion rate for humeral shaft fractures was 32% for patients older than 55 years. The authors found a significant correlation between age and union rate: as age increased, union rate decreased (R=-0.9, P=.045). The incidence of humeral shaft nonunion in patients older than 55 years was significantly higher than that of younger adults. To the authors' knowledge, this study is the first to report a significant correlation between nonunion and increased age. [Orthopedics. 2020;43(3);168-172.].
非手术治疗已成为大多数肱骨干骨折的标准治疗方法。已发表的研究主要来自拥有年轻患者群体的创伤中心。本研究的目的是确定55岁以上患者肱骨干骨折的不愈合率。对在一级创伤中心接受治疗的一组骨科创伤患者进行了为期10年(2007 - 2017年)的回顾性研究。确定了年龄在55岁及以上且接受肱骨干骨折非手术治疗(无论是否进行手法复位)的患者。不愈合的定义为伤后至少12周影像学上无骨痂桥接或骨折处有明显活动。共有31例符合纳入标准的肱骨干骨折患者。该队列包括21名(67.7%)女性和10名(32.3%)男性,平均年龄为72.5岁(范围55 - 92岁)。21例骨折实现愈合,10例不愈合,在人口统计学或合并症方面无显著差异。AO/OTA骨折分类或骨折部位与愈合状态之间无相关性。与肱骨干中段(26%)和远端(20%)骨折相比,近端三分之一肱骨干骨折的不愈合风险有升高趋势(45%),尽管这在统计学上无显著意义。55岁以上患者肱骨干骨折的总体不愈合率为32%。作者发现年龄与愈合率之间存在显著相关性:随着年龄增加,愈合率下降(R = -0.9,P = 0.045)。55岁以上患者肱骨干不愈合的发生率明显高于年轻成年人。据作者所知,本研究是首个报道不愈合与年龄增加之间存在显著相关性的研究。[《骨科》。2020;43(3);168 - 172。]