Paediatric Dentistry Postgraduate Program, Faculty of Dentistry, San Luis Potosi University, San Luis Potosi, SLP, Mexico.
Basic Sciences Laboratory, Faculty of Dentistry, San Luis Potosi University, San Luis Potosi, SLP, Mexico.
Int J Paediatr Dent. 2020 Sep;30(5):536-546. doi: 10.1111/ipd.12633. Epub 2020 Mar 9.
To summarize the clinical/radiographic outcomes from the evidence of studies published since 1988 on different DPC agents applied on vital pulp-exposed primary teeth.
The following electronic databases were searched: PubMed, Embase, Cochrane Library, Dentistry and Oral Science Source, and Google Scholar. Inclusion criteria were randomized controlled trials (RCTs) published between January 1988 and December 2019, with at least 6 months of follow-up, comparing the clinical and radiographic success rates of two or more DPC agents applied in primary teeth with cariously and non-cariously exposed pulp.
Initial searches identified 83 potentially relevant studies on DPC in primary teeth. Sixty-four of these studies were excluded, whereas 19 articles satisfied the inclusion criteria and were retrieved in full text for data extraction and a methodological quality assessment. Finally, 12 of these articles were included in the systematic review. Low and moderate risks of bias were observed. Overall, DPC clinical and radiographic success rates among the selected studies ranged between 53% and 100%.
For DPC in primary teeth, this systematic review found that diverse new biologically and compatible agents with promising success rates are currently available for paediatric dentistry practitioners. There is no evidence that justifies discarding the judicious use of DPC procedures in primary teeth.
总结自 1988 年以来发表的关于应用于活髓暴露的乳牙的不同 DPC 制剂的研究证据的临床/影像学结果。
检索以下电子数据库:PubMed、Embase、Cochrane 图书馆、牙科和口腔科学源以及 Google Scholar。纳入标准为 1988 年 1 月至 2019 年 12 月期间发表的随机对照试验(RCT),随访时间至少 6 个月,比较两种或多种 DPC 制剂在有龋和无龋暴露牙髓的乳牙中的临床和影像学成功率。
最初的检索确定了 83 项关于乳牙中 DPC 的潜在相关研究。其中 64 项研究被排除,而 19 篇文章符合纳入标准,并全文检索以提取数据和进行方法学质量评估。最后,有 12 篇文章被纳入系统评价。观察到低和中度偏倚风险。总体而言,所选研究中 DPC 的临床和影像学成功率在 53%至 100%之间。
对于乳牙中的 DPC,本系统评价发现,目前有许多新的生物相容性制剂具有有前途的成功率,可供儿科牙医使用。没有证据表明可以放弃在乳牙中合理使用 DPC 程序。