Korkmaz Ulku, Ustun Funda
Trakya University Faculty of Medicine, Department of Nuclear Medicine, Edirne, Turkey
Mol Imaging Radionucl Ther. 2020 Feb 17;29(1):41-44. doi: 10.4274/mirt.galenos.2019.85547.
With the increase in the diagnosis of the cancer, the frequency of using imaging methods for diagnosis and for staging is also increased. Because of the complex structure of cancer and tumor behavior, the assessment methods have been updated and metabolic imaging has gained weight. The most popular of these techniques is hybrid positron emission tomography/computed tomography (PET/CT) systems. Prostate cancer is the second most common cancer in the world, is the fifth common type in cancer-related male deaths. Estimation of prognosis and treatment planning of the patients are based on the TNM classification. Bone metastasis is a prognostic factor of morbidity and mortality in prostate cancer. Sodium fluoride (NaF) PET/CT is a promising imaging modality in evaluation of skeletal system. This article will review the involvement of F-NaF in extra-osseous tissues in the prostate cancer and reveal the fundamental differences between F-NaF imaging and F-FDG imaging in these areas.
随着癌症诊断率的提高，用于诊断和分期的成像方法的使用频率也在增加。由于癌症结构复杂且肿瘤行为多样，评估方法不断更新，代谢成像的重要性日益凸显。这些技术中最受欢迎的是正电子发射断层扫描/计算机断层扫描（PET/CT）系统。前列腺癌是世界上第二常见的癌症，在与癌症相关的男性死亡中位列第五。患者的预后评估和治疗方案制定基于TNM分类。骨转移是前列腺癌发病和死亡的一个预后因素。氟化钠（NaF）PET/CT是评估骨骼系统的一种有前景的成像方式。本文将综述F-NaF在前列腺癌骨外组织中的累及情况，并揭示这些区域中F-NaF成像与F-FDG成像之间的根本差异。
