Nichelli P, Bahmanian-Behbahani G, Gentilini M, Vecchi A
Clinica Neurologica, Università di Modena, Italy.
Brain. 1988 Dec;111 ( Pt 6):1337-53. doi: 10.1093/brain/111.6.1337.
The pattern of preserved learning abilities is described in a severely amnesic patient after bilateral thalamic infarction. Experimental findings cannot be accounted for both by the view that only episodic memory is impaired in amnesia, while semantic memory is spared, and by the theory that what is spared in amnesia is procedural learning contrasted with impaired declarative memory. In agreement with Warrington and Weiskrantz (1982), diencephalic amnesia is considered to be a disconnection syndrome between the frontal and temporal lobes. The conditions for showing spared and impaired memory in amnesics are specified on the basis of the performance of the patient and of the data available in the literature. This allows us to derive practical suggestions for programmes aimed at remediation of memory defects.
本文描述了一名双侧丘脑梗死所致严重失忆患者保留学习能力的模式。实验结果无法用以下两种观点来解释:一种观点认为,失忆症仅损害情景记忆,而语义记忆不受影响;另一种理论认为,失忆症中保留的是程序性学习,与之形成对比的是受损的陈述性记忆。与沃林顿和韦斯克兰茨(1982年)的观点一致,间脑失忆症被认为是额叶和颞叶之间的一种分离综合征。根据该患者的表现以及文献中的现有数据,明确了失忆症患者表现出记忆保留和受损的条件。这使我们能够为旨在修复记忆缺陷的方案得出实用建议。