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基线特征可能有助于为初级保健中的背痛患者指明最佳医疗服务提供者选择:一项前瞻性队列研究的结果

Baseline Characteristics May Help Indicate the Best Choice of Health Care Provider for Back Pain Patients in Primary Care: Results From a Prospective Cohort Study.

作者信息

Hartvigsen Lisbeth, Kongsted Alice, Vach Werner, Salmi Louis-Rachid, Hestbaek Lise

机构信息

Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.

Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark; Nordic Institute of Chiropractic and Clinical Biomechanics, Odense, Denmark.

出版信息

J Manipulative Physiol Ther. 2020 Jan;43(1):13-23. doi: 10.1016/j.jmpt.2019.11.001. Epub 2020 Feb 17.

Abstract

OBJECTIVE

Baseline characteristics of patients low back pain differ substantially between care settings, but it is largely unknown whether predictors are of equal importance across settings. The aim of this study was to investigate whether 8 known predictors relate differently to outcomes in chiropractic practice and in general practice and to which degree these factors may be helpful in selecting patients benefiting more from one setting or the other.

METHODS

Patient characteristics were collected at baseline, and outcomes of pain intensity (numeric rating scale 0-10) and activity limitation (Roland-Morris Disability Questionnaire 0-100) after 2, 12, and 52 weeks. Differences in the prognostic strength between settings were investigated for each prognostic factor separately by estimating the interaction between setting and the prognostic factor using regression models. Between-setting differences in outcome in high-risk and low-risk subgroups, formed by single prognostic factors, were assessed in similar models adjusted for a propensity score to take baseline differences between settings into account.

RESULTS

Prognostic factors were generally associated more strongly with outcomes in general practice compared with chiropractic practice. The difference was statistically significant for general health, duration of pain, and musculoskeletal comorbidity. After propensity score adjustment, differences in outcomes between settings were insignificant, but negative prognostic factors tended to be less influential in chiropractic practice except for leg pain and depression, which tended to have less negative impact in general practice.

CONCLUSION

Known prognostic factors related differently to outcomes in the 2 settings, suggesting that some subgroups of patients might benefit more from one setting than the other.

摘要

目的

腰痛患者的基线特征在不同护理环境中存在很大差异,但对于预测因素在不同环境中是否具有同等重要性,目前尚不清楚。本研究的目的是调查8个已知的预测因素在整脊疗法实践和全科医疗实践中与治疗结果的关系是否不同,以及这些因素在多大程度上有助于选择从一种环境或另一种环境中获益更多的患者。

方法

在基线时收集患者特征,并在2周、12周和52周后收集疼痛强度(数字评分量表0-10)和活动受限(罗兰-莫里斯残疾问卷0-100)的结果。通过使用回归模型估计环境与预测因素之间的相互作用,分别对每个预测因素在不同环境中的预后强度差异进行调查。在考虑环境间基线差异的倾向得分调整的类似模型中,评估由单一预测因素形成的高风险和低风险亚组在不同环境中的结果差异。

结果

与整脊疗法实践相比,预测因素在全科医疗实践中通常与结果的关联更强。在总体健康、疼痛持续时间和肌肉骨骼合并症方面,差异具有统计学意义。经过倾向得分调整后,不同环境间的结果差异不显著,但除腿痛和抑郁外,负面预测因素在整脊疗法实践中的影响往往较小,而腿痛和抑郁在全科医疗实践中的负面影响往往较小。

结论

已知的预测因素在两种环境中与结果的关系不同,这表明某些患者亚组可能从一种环境中比从另一种环境中获益更多。

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