Tripathi Richa, Rao Ravindra, Dhawan Anju, Jain Raka, Sinha Sanjeev
D.M. Addiction Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Department of Psychiatry and National Drug Dependence Treatment Center, All India Institute of Medical Sciences, New Delhi, India.
Sleep Med. 2020 Mar;67:269-275. doi: 10.1016/j.sleep.2019.06.012. Epub 2019 Jul 3.
Sleep is an evolutionarily conserved process and is important for rest and recovery of various biological functions. Sleep and alertness alterations, function as contributing/modulatory factors in initiating and maintaining drug and alcohol abuse and as factors that increase the risk for relapse. Opioid dependent individuals frequently complain of sleep problems during withdrawal and abstinence. Sleep disturbances are seen even among patients on opioid substitution therapy (OST). The aim of this review is to present an overview of sleep problems in opioid dependent patients and to delineate factors associated with sleep disturbance.
睡眠是一个进化上保守的过程，对各种生物功能的休息和恢复很重要。睡眠和警觉性改变，在引发和维持药物及酒精滥用中起促成/调节因素的作用，也是增加复发风险的因素。阿片类药物依赖个体在戒断和禁欲期间经常抱怨睡眠问题。即使在接受阿片类药物替代疗法（OST）的患者中也会出现睡眠障碍。这篇综述的目的是概述阿片类药物依赖患者的睡眠问题，并描述与睡眠障碍相关的因素。
