Rustempasic Nedzad, Semi Selma
Clinic for Cardiovascular Surgery, Clinical Center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Mater Sociomed. 2019 Dec;31(4):273-276. doi: 10.5455/msm.2019.31.273-276.
Abdominal aortic aneurysm represents a local pathological dilatation of the abdominal aorta. It is caused by structural weakness of aortic wall but there are many other risk factors that may positively correlate with incidence of AAA like hypertension, smoking, male gender, older age, family history etc.
The purpose of the study was to evaluate the correlation of atherosclerotic risk factors and the size of aortic aneurysm in patients that were admitted for the surgical treatment at the Clinic for cardiovascular surgery in Sarajevo during period 2016-2019.
The study was designed as a retrospective study with one group of patients that was conducted at the Clinical Center of the University of Sarajevo at the Clinic for Cardiovascular Surgery. It included 150 patients, 126 males and 24 females, all of them with infrarenal localization of AAA. From medical records we have collected relevant anamnestic data (age, gender, positive family history, diabetes mellitus, hypertension, hyperlipidemia, smoking, alcohol consumption and obesity). The size of aneurysm was determined by both ultrasound and CT arteriography. The data are processed in the Statistical Package for Social Sciences Ver. 22.0. The results are tabulated or graphically showed, and level of statistical significance was set at p <0.05.
Total amount of 129 of patients (86%) had hypertension, 57.3% (n=86) of them were smokers, 18.7% (n = 28) were former smokers, and 24% (n = 36) were non-smokers Blood lipid level analysis have shown that 44% (n = 66) of patients were normolipemic, while elevated blood lipid levels were found in 56% (n = 84) of patients. Diabetes mellitus was present in 17.3% (n = 26) of patients, 2.7% (n = 4) of them had an insulin-dependent form, while 14.7% (n = 22) of the analyzed patients had insulin independent DM. Almost half of total number of patients (46%, n = 69) were obese. 19.3% (n = 29) of patients consumed alcohol while the 80.7% (n = 121) denied alcohol consumption. Ratio of males in comparison to females was 5:1. The average age in males was 69.79 ± 8.16 years and 72.13 ± 9.11 years in females. Significant statistical correlation of AAA size and risk of atherosclerosis factor has not been established. We have found that there is a significant positive correlation between size of aneurysm and risk of rupture (p= 0,000<0,05).
Although risk factors of atherosclerosis were present, statistically positive correlation was not confirmed between the size of AAA and analyzed risk factors.
腹主动脉瘤是腹主动脉的局部病理性扩张。它由主动脉壁结构薄弱引起，但还有许多其他风险因素可能与腹主动脉瘤的发病率呈正相关，如高血压、吸烟、男性、高龄、家族病史等。
本研究的目的是评估2016年至2019年期间在萨拉热窝心血管外科诊所接受手术治疗的患者中动脉粥样硬化风险因素与主动脉瘤大小的相关性。
本研究设计为对一组患者的回顾性研究，在萨拉热窝大学临床中心心血管外科诊所进行。研究纳入了150例患者，其中男性126例，女性24例，所有患者的腹主动脉瘤均位于肾下。我们从病历中收集了相关的既往病史数据（年龄、性别、家族史阳性、糖尿病、高血压、高脂血症、吸烟、饮酒和肥胖）。通过超声和CT血管造影确定动脉瘤的大小。数据在社会科学统计软件包22.0版中进行处理。结果以表格或图表形式呈现，统计学显著性水平设定为p<0.05。
共有129例患者（86%）患有高血压，其中57.3%（n=86）为吸烟者，18.7%（n=28）为既往吸烟者，24%（n=36）为非吸烟者。血脂水平分析显示，44%（n=66）的患者血脂正常，而56%（n=84）的患者血脂水平升高。17.3%（n=26）的患者患有糖尿病，其中2.7%（n=4）为胰岛素依赖型，而14.7%（n=22）的分析患者为非胰岛素依赖型糖尿病。几乎一半的患者（46%，n=69）肥胖。19.3%（n=29）的患者饮酒，而80.7%（n=121）的患者否认饮酒。男性与女性的比例为5:1。男性的平均年龄为69.79±8.16岁，女性为72.13±9.11岁。未发现腹主动脉瘤大小与动脉粥样硬化风险因素之间存在显著的统计学相关性。我们发现动脉瘤大小与破裂风险之间存在显著的正相关（p=0.000<0.05）。
尽管存在动脉粥样硬化风险因素，但腹主动脉瘤大小与分析的风险因素之间未证实存在统计学上的正相关。
