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一名67岁男性,伴有弥漫性紫癜性水疱和大疱。

A 67-Year-Old Male with Diffuse Purpuric Vesicles and Bullae.

作者信息

Yu Zizi, Xue Yun, Foreman Ruth, Kroshinsky Daniela

机构信息

Harvard Medical School, Boston, Massachusetts, USA.

Harvard Combined Dermatology Residency Training Program and Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Dermatopathology (Basel). 2020 Jan 24;6(4):251-254. doi: 10.1159/000503662. eCollection 2019 Oct-Dec.

Abstract

Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis that most commonly affects the postcapillary venules in the skin. It classically presents with purpuric macules that progress to palpable purpura on the bilateral shins 7-10 days after an inciting medication or infection, or in the setting of connective tissue disease, malignancy, or inflammatory bowel disease. Up to 50% of cases have no identifiable cause. Lesions on the buttocks, abdomen, upper extremities, and face are uncommon, as are bullae and ulcers. We present a rare case of bullous LCV manifesting as grouped vesicles on the face and body mimicking varicella-zoster infection.

摘要

白细胞破碎性血管炎(LCV)是一种小血管炎,最常累及皮肤的毛细血管后微静脉。典型表现为紫癜性斑疹,在诱发药物或感染后7 - 10天,或在结缔组织病、恶性肿瘤或炎症性肠病的情况下,双侧小腿会进展为可触及的紫癜。高达50%的病例病因不明。臀部、腹部、上肢和面部的病变不常见,大疱和溃疡也不常见。我们报告一例罕见的大疱性LCV病例,表现为面部和身体上成簇的水疱,酷似水痘 - 带状疱疹感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1512/7011730/e2ca251d23b2/dpa-0006-0251-g01.jpg

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