Yu Zizi, Xue Yun, Foreman Ruth, Kroshinsky Daniela
Harvard Medical School, Boston, Massachusetts, USA.
Harvard Combined Dermatology Residency Training Program and Harvard Medical School, Boston, Massachusetts, USA.
Dermatopathology (Basel). 2020 Jan 24;6(4):251-254. doi: 10.1159/000503662. eCollection 2019 Oct-Dec.
Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis that most commonly affects the postcapillary venules in the skin. It classically presents with purpuric macules that progress to palpable purpura on the bilateral shins 7-10 days after an inciting medication or infection, or in the setting of connective tissue disease, malignancy, or inflammatory bowel disease. Up to 50% of cases have no identifiable cause. Lesions on the buttocks, abdomen, upper extremities, and face are uncommon, as are bullae and ulcers. We present a rare case of bullous LCV manifesting as grouped vesicles on the face and body mimicking varicella-zoster infection.
白细胞破碎性血管炎(LCV)是一种小血管炎,最常累及皮肤的毛细血管后微静脉。典型表现为紫癜性斑疹,在诱发药物或感染后7 - 10天,或在结缔组织病、恶性肿瘤或炎症性肠病的情况下,双侧小腿会进展为可触及的紫癜。高达50%的病例病因不明。臀部、腹部、上肢和面部的病变不常见,大疱和溃疡也不常见。我们报告一例罕见的大疱性LCV病例,表现为面部和身体上成簇的水疱,酷似水痘 - 带状疱疹感染。