Department of Pharmacy, Barnes-Jewish Hospital, Saint Louis, Missouri, USA.
Department of Pharmacy Services, Michigan Medicine, Ann Arbor, Michigan, USA.
Nutr Clin Pract. 2021 Apr;36(2):418-426. doi: 10.1002/ncp.10469. Epub 2020 Feb 21.
Parenteral nutrition (PN) is a complex therapy with numerous opportunities for error during the prescribing, preparation, and administration processes. Advances in technology, such as computerized provider order entry (CPOE), electronic health records (EHRs), and clinical decision support (CDS) have helped decrease the risks associated with PN therapy. These technologies can be utilized to guide prescribing, provide automated safety checks, and increase overall safety and accuracy in PN ordering, compounding, and administration. In recent years, increased awareness of the risks associated with PN therapy, in particular issues with ordering and transcription, have magnified the need for improved support of PN ordering within currently available systems. Additionally, drug shortages continue to impact key components of PN admixtures, further increasing the risks associated with this complex therapy. These concerns and risks present an opportunity for the development of new functionality, as well as improvements in and innovative utilization of available technology within systems supporting the PN use process. This discussion will highlight the risks associated with PN, examine the role of drug shortages on the safety of this therapy, describe the application of available technology to manage shortages, and report the experience of using commercially available CDS tools at one academic medical center. It will also include a discussion of the transition from paper orders to CPOE/EHR-based orders for PN and the transition from one commercially available electronic system to another at this particular institution.
肠外营养(PN)是一种复杂的治疗方法,在处方、准备和管理过程中有许多出错的机会。技术的进步,如计算机化医嘱录入(CPOE)、电子健康记录(EHR)和临床决策支持(CDS),有助于降低与 PN 治疗相关的风险。这些技术可用于指导处方、提供自动安全检查,并提高 PN 医嘱、配制和管理的整体安全性和准确性。近年来,人们越来越意识到 PN 治疗相关的风险,特别是在医嘱和转录方面的问题,这凸显了在现有系统中改进 PN 医嘱支持的必要性。此外,药物短缺继续影响 PN 混合物的关键成分,进一步增加了这种复杂治疗的风险。这些问题和风险为新功能的开发以及现有系统中支持 PN 使用过程的技术的改进和创新利用提供了机会。本文将重点讨论 PN 相关的风险,研究药物短缺对该治疗安全性的影响,描述现有技术在管理短缺方面的应用,并报告在一家学术医疗中心使用商业可用的 CDS 工具的经验。本文还将讨论从纸质医嘱到基于 CPOE/EHR 的 PN 医嘱的转变,以及在该机构从一个商业上可用的电子系统到另一个电子系统的转变。