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人类免疫缺陷病毒与全身结核分枝杆菌合并感染患者的眼部结核。

Ocular Tuberculosis in Human Immunodeficiency Virus and Systemic Tuberculosis Co-infected Patients.

机构信息

Advanced Eye Center, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Ocul Immunol Inflamm. 2021 Jul 4;29(5):1002-1006. doi: 10.1080/09273948.2020.1714059. Epub 2020 Feb 21.

Abstract

: To describe the prevalence and clinical findings of ocular tuberculosis (TB) in Human immunodeficiency virus (HIV) and systemic TB co-infected patients.: In this prospective, observational, non-comparative case series, we included HIV and systemic TB co-infected patients, who underwent a detailed ophthalmic and systemic evaluation.: Of 85 patients, ocular tuberculosis was seen in eleven patients and their 16 eyes (12.9%). Without the benefit of eye exam, the diagnosis of disseminated TB was missed in 5/52 (9.6%) and 2/25 (8%) of patients clinically assumed to have pulmonary and Extrapulmonary TB, respectively.: HIV patients with the disseminated TB have higher risk for ocular TB. As ocular symptoms are rare, still all of them need a detailed ocular examination to look for active ocular TB which will reclassify isolated pulmonary/extrapulmonary to disseminated TB warranting a detailed systemic examination.

摘要

: 描述人类免疫缺陷病毒(HIV)和系统性结核(TB)合并感染患者眼部结核(TB)的流行率和临床发现。: 在这项前瞻性、观察性、非对照病例系列研究中,我们纳入了 HIV 和系统性 TB 合并感染的患者,他们接受了详细的眼部和全身评估。: 在 85 名患者中,11 名患者的 16 只眼(12.9%)出现眼部结核。如果没有眼部检查,5/52(9.6%)和 2/25(8%)分别被临床诊断为肺结核和肺外结核的患者的播散性结核诊断将被遗漏。: 患有播散性结核的 HIV 患者患眼部结核的风险更高。由于眼部症状罕见,所有患者仍需要进行详细的眼部检查,以寻找活动性眼部结核,这将重新分类为孤立性肺结核/肺外结核为播散性结核,需要进行详细的全身检查。

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