Lima Luiz H, Melo Gustavo B, Zett Claudio, Morais Fábio B, Leal Bruno C, Farah Michel E, Belfort Rubens
Ophthalmic Surg Lasers Imaging Retina. 2020 Feb 1;51(2):76-83. doi: 10.3928/23258160-20200129-02.
To report a unique case series of diffuse unilateral subacute neuroretinitis (DUSN) patients imaged with optical coherence tomography angiography (OCTA).
In this retrospective case series, multimodal imaging was performed in four patients with DUSN at the time of patient visit. The study patients underwent standard clinical treatment for DUSN.
The clinical findings were consistent with the diagnosis of DUSN. Cross-sectional OCT showed disruption of outer retinal layers in the foveal area and an irregular structure of the outer plexiform layer. En face OCT revealed hyperreflective spots and a large hyperreflective lesion in the foveal area correspondent to the outer retina disruption seen on cross-sectional OCT. OCTA demonstrated decreased vascular perfusion in both the superficial and deep retinal capillary plexuses along with choriocapillaris preservation.
OCTA may provide a more detailed assessment of the retinal microvascular changes, allowing a more precise anatomical-functional correlation in DUSN. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:76-83.].
报告一组采用光学相干断层扫描血管造影（OCTA）成像的弥漫性单侧亚急性神经视网膜炎（DUSN）患者的独特病例系列。
在这个回顾性病例系列中，对4例DUSN患者就诊时进行了多模态成像检查。研究患者接受了DUSN的标准临床治疗。
临床检查结果与DUSN的诊断一致。横断面光学相干断层扫描（OCT）显示黄斑区视网膜外层中断，外网状层结构不规则。正面OCT显示黄斑区有高反射点和一个大的高反射病变，与横断面OCT上所见的视网膜外层中断相对应。OCTA显示视网膜浅层和深层毛细血管丛的血管灌注减少，同时脉络膜毛细血管保持完好。
OCTA可能对视网膜微血管变化提供更详细的评估，从而在DUSN中实现更精确的解剖-功能相关性分析。[《眼科手术、激光与视网膜成像》。2020；51：76 - 83。]
