Gao Bingqiang, Zhou Dongkai, Qian Xiaohui, Zhang Wang, Ying Lixiong, Wang Weilin
Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Cardiovasc Pathol. 2020 May-Jun;46:107097. doi: 10.1016/j.carpath.2018.11.003. Epub 2018 Dec 4.
Benign smooth muscle tumors of the inferior vena cava (IVC) are unusual, but mostly consist of intravenous leiomyomatosis, which arises from the uterus. Primary leiomyoma of the IVC is extremely rare. Here, we report a primary leiomyoma of the IVC, misleadingly reported as a cystic neoplasm of the pancreas in images. Immunohistochemical analysis was positive for (estrogen receptor) ER and (progesterone receptor) PR, indicating gynecologic leiomyomas. The use of ER and PR immunostaining is recommended to help distinguish between somatic and gynecologic leiomyomas, whose criteria of malignancy differ.
下腔静脉(IVC)的良性平滑肌肿瘤较为罕见,但大多由源自子宫的静脉内平滑肌瘤病组成。IVC原发性平滑肌瘤极为罕见。在此,我们报告一例IVC原发性平滑肌瘤,在影像学上曾被误诊为胰腺囊性肿瘤。免疫组化分析显示雌激素受体(ER)和孕激素受体(PR)呈阳性,提示为妇科平滑肌瘤。建议使用ER和PR免疫染色来帮助区分体细胞性和平滑肌瘤,因为它们的恶性标准不同。