van Eyck J, Wladimiroff J W, Noordam M J, Cheung K L, van den Wijngaard J A, Prechtl H F
Department of Obstetrics and Gynaecology, Erasmus University Rotterdam, The Netherlands.
Early Hum Dev. 1988 Aug-Sep;17(2-3):187-94. doi: 10.1016/0378-3782(88)90007-2.
In 13 normal pregnancies at 27-28 weeks of gestation the blood flow velocity waveform at the lower thoracic level of the fetal descending aorta was studied in relation to fetal heart rate pattern (FHRP), fetal eye movements (FEM) and fetal body movements (FBM). State parameter combinations in which high fetal heart rate (FHR) variability was present, were associated with a significant reduction in pulsatility index (PI) as compared with periods in which low FHR variability was present, irrespective of FEM and FBM, indicating a reduced peripheral vascular resistance. At 27-28 weeks of gestation FHR variability and PI might be linked to baroreceptor sensitivity. PI values derived from combinations FHRP-A, FEM(-), FBM(-) and FHRP-B, FEM(+), FBM(+) showed a significant inverse relationship (P less than 0.05) with FHR. FHR and FHR variability should be taken into account when studying flow velocity waveforms in the fetal descending aorta at 27-28 weeks of gestation.
在13例妊娠27 - 28周的正常妊娠中，研究了胎儿降主动脉下胸部水平的血流速度波形与胎儿心率模式（FHRP）、胎儿眼动（FEM）和胎儿身体运动（FBM）的关系。与存在低胎儿心率（FHR）变异性的时期相比，存在高胎儿心率变异性的状态参数组合与搏动指数（PI）的显著降低相关，无论FEM和FBM如何，这表明外周血管阻力降低。在妊娠27 - 28周时，FHR变异性和PI可能与压力感受器敏感性有关。从FHRP - A、FEM（-）、FBM（-）和FHRP - B、FEM（+）、FBM（+）组合得出的PI值与FHR呈显著负相关（P小于0.05）。在研究妊娠27 - 28周胎儿降主动脉的血流速度波形时，应考虑FHR和FHR变异性。
