Nastenko E P, Drozdova V D, Bebeshko V G, Koval' A I
Eksp Onkol. 1988;10(5):61-4.
Ultrastructural peculiarities of stromal elements from bone marrow and endosteum in 28 children with acute leukaemia during clinical and hematological exacerbations are presented. Investigations are conducted before chemotherapy. Changes in ultrastructure of all stromal components are revealed. Of special significance are the data on variations of reticular cells and rough desorganization of fibrillar structures. Disturbances in intercellular contacts between hemopoietic cells and stromal elements are detected.
本文呈现了28例急性白血病患儿在临床和血液学加重期骨髓及骨内膜基质成分的超微结构特征。研究在化疗前进行。所有基质成分的超微结构均有改变。网状细胞的变化及纤维结构的明显紊乱数据具有特殊意义。造血细胞与基质成分之间的细胞间接触存在干扰。
