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[全身性霍奇金病患者治疗期间脾脏结构的变化]

[Changes in the spleen structure during treatment of patients with generalized Hodgkin's disease].

作者信息

Gubareva A V, Markochev A B, Simbirtseva L P, Asaturian M A

出版信息

Eksp Onkol. 1988;10(5):70-3.

PMID:3208697
Abstract

Data obtained from 35 autopsies and morphological examination of the irradiated and non-irradiated spleen are analyzed. Morphological changes in the spleen as a result of radiation are described. Curability of Hodgkin's disease foci is established to be possible in the spleen irradiated with the dose of 35-40 Gy. A prophylactic spleen irradiation decreases the possibility of its metastatic damage in generalized Hodgkin's disease.

摘要

对35例尸体解剖以及对受照射和未受照射脾脏进行形态学检查所获得的数据进行了分析。描述了辐射导致的脾脏形态学变化。确定在接受35 - 40 Gy剂量照射的脾脏中,霍奇金病病灶有可能治愈。预防性脾脏照射可降低全身性霍奇金病中脾脏发生转移损害的可能性。

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