Oakovlev A I, Konoplia A I, Laskova I L, Kedrovskaia N N
Farmakol Toksikol. 1988 Sep-Oct;51(5):68-72.
In experiments on Wistar rats it was found that oral administration of heteropolysaccharide preparations isolated from medicinal plants of Asteraceae, Tiliaceae and Polygonaceae families induces the appearance in the blood serum and supernatant fluid of cells of the spleen and thymus of humoral immunostimulating substances. Similar factors appear in the supernatant fluid of cells of the spleen and thymus after their treatment with sera of the rats receiving polysaccharides. The administration of the preparations significantly changes the appearance of the immunostimulating factors in animals with the toxic liver damage as well as under intensive physical exercise.