尼日利亚中部某地区医院的皮肤及软组织病变：一项组织病理学研究

Skin and Soft Tissue Lesions in a District Hospital in Central Nigeria: A Histopathological Study.

作者信息

Duduyemi Babatunde M, Omonisi Abidemi E, Titiloye Nicholas A

机构信息

Department of Pathology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Department of Pathology, Asokoro District Hospital, Abuja, Nigeria.

出版信息

Dermatol Res Pract. 2019 Dec 26;2019:8143680. doi: 10.1155/2019/8143680. eCollection 2019.

DOI:10.1155/2019/8143680

PMID:32089672

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7012205/

Abstract

UNLABELLED

. Skin and soft tissue diseases form a large and heterogeneous group of mesenchymal extraskeletal and dermatologic lesions in humans. Diseases of the skin and soft tissue can develop virtually anywhere in the body, extremities, the trunk, the retroperitoneum, the head, and the neck. Our study aims to review skin and soft tissue specimens from our centre describing the histopathological patterns.

METHOD

A cross sectional study was done using secondary data of all skin and soft tissue specimens over a 3 year period. Patients' demographics, sites of specimen, and histological diagnoses were extracted from the surgical day book. The data were analysed in terms of age and sex distribution and histological characteristics of pathologic lesions using the SPSS version 22. The data for these patients were presented in tables and figures.

RESULT

451 skin and soft tissue specimens constituting 18% of all the specimens with an M : F ratio of 1 : 1.2. The age range of our patients was 4-85 years with a mean of 33.52 ± 15.05 years. The peak age of occurrence was 30-39 years. Most of our cases were seen in the extremities (50.7%) followed by head (22.2%), while the least common sites were the perineal and neck areas (5.3% each). The commonest site in females was the upper limb (32.4%); the head and lower limb were the commonest sites in males (28.4% each). Most of our patients have neoplastic lesions of skin and soft tissue constituting 68.3%, inflammatory lesions (16.9%), and the least common lesion being hamartoma (0.2%). The most common category of lesions includes inflammatory (nonspecific dermatitis 6.5%); cysts (dermoid cyst 6%); reactive (hypertrophic scar 1%); and neoplastic (lipoma 32.4%). The benign neoplasms were more common (92.9%) than the malignant ones (7.1%). The neoplastic lesions were relatively more common in males than females and the reverse was true for the inflammatory lesions.

CONCLUSION

Skin and soft tissue lesions are relatively common in our environment with majority being benign neoplastic lesion.

摘要

未标注

皮肤和软组织疾病构成了人类间充质骨骼外和皮肤病损的一个庞大且异质性的群体。皮肤和软组织疾病几乎可发生于身体的任何部位，如四肢、躯干、腹膜后、头部和颈部。我们的研究旨在回顾我们中心的皮肤和软组织标本，描述其组织病理学模式。

方法

采用一项横断面研究，使用3年期间所有皮肤和软组织标本的二手数据。从手术日志中提取患者的人口统计学信息、标本部位和组织学诊断。使用SPSS 22版对数据进行年龄和性别分布以及病理病变组织学特征方面的分析。这些患者的数据以表格和图表形式呈现。

结果

451例皮肤和软组织标本，占所有标本的18%，男女比例为1∶1.2。我们患者的年龄范围为4至85岁，平均年龄为33.52±15.05岁。发病高峰年龄为30至39岁。我们的大多数病例见于四肢（50.7%），其次是头部（22.2%），而最不常见的部位是会阴和颈部区域（各占5.3%）。女性最常见的部位是上肢（32.4%）；男性最常见的部位是头部和下肢（各占28.4%）。我们的大多数患者患有皮肤和软组织肿瘤性病变，占68.3%，炎症性病变（16.9%），最不常见的病变是错构瘤（0.2%）。最常见的病变类别包括炎症性（非特异性皮炎6.5%）；囊肿（皮样囊肿6%）；反应性（肥厚性瘢痕1%）；以及肿瘤性（脂肪瘤3******%）。良性肿瘤比恶性肿瘤更常见（92.9%对7.1%）。肿瘤性病变在男性中相对比女性更常见，而炎症性病变则相反。