Davis Daniel E, Zmistowski Benjamin, Abboud Joseph A, Namdari Surena
Department of Orthopaedic Surgery, The Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Arch Bone Jt Surg. 2020 Jan;8(1):38-43. doi: 10.22038/abjs.2018.34938.1918.
Laminar flow ventilation systems were developed to reduce surgical contamination in joint arthroplasty to avoid periprosthetic joint infection (PJI). The goals of this study are to evaluate the cost-effectiveness and economic viability of installing and maintaining a laminar flow system in an operating room.
A Monte Carlo simulation was used to evaluate the cost effectiveness of laminar flow. The variables included were cost to treat PJI, incidence of PJI, cost of laminar flow, years of operating room use, and arthroplasty volume as the dependent variable.
Laminar flow would be financially-justified when 1,217 (SD: 319) TSA cases are performed annually with assumed 10% reduction in PJI from laminar flow and 487 (SD: 127) with assumed 25% reduction. In a high volume OR, laminar flow costs $25.24 per case (assuming 10% reduction) and $8.24 per case (assuming 25% reduction). Laminar flow would need to reduce the incidence of PJI by 35.1% (SD: 9.1) to be a cost-effective strategy.
This analysis demonstrates the substantial arthroplasty volume and large reduction in PJI rates required to justify the installation and maintenance costs of this technology. This high cost of implementation should be considered prior to installing laminar flow systems.
层流通风系统的开发旨在减少关节置换术中的手术污染,以避免假体周围关节感染(PJI)。本研究的目的是评估在手术室安装和维护层流系统的成本效益和经济可行性。
采用蒙特卡罗模拟来评估层流的成本效益。纳入的变量包括治疗PJI的成本、PJI的发生率、层流的成本、手术室使用年限以及作为因变量的关节置换手术量。
当每年进行1217例(标准差:319)全髋关节置换(THA)手术且假设层流使PJI减少10%时,以及每年进行487例(标准差:127)手术且假设层流使PJI减少25%时,层流在经济上是合理的。在高手术量的手术室中,层流每例手术成本为25.24美元(假设减少10%)和8.24美元(假设减少25%)。层流需要将PJI的发生率降低35.1%(标准差:9.1)才能成为具有成本效益的策略。
该分析表明,要证明这项技术的安装和维护成本合理,需要大量的关节置换手术量以及大幅降低PJI发生率。在安装层流系统之前,应考虑这种高昂的实施成本。