Victora C G, Smith P G, Vaughan J P, Nobre L C, Lombardi C, Teixeira A M, Fuchs S C, Moreira L B, Gigante L P, Barros F C
Departamento de Medicina Social, Faculdade de Medicina, Universidade Federal de Pelotas, Brazil.
Int J Epidemiol. 1988 Sep;17(3):651-4. doi: 10.1093/ije/17.3.651.
In a population-based case-control study in the metropolitan areas of Porto Alegre and Pelotas in southern Brazil children dying in infancy from diarrhoea were compared to neighbourhood controls in terms of several social and environmental variables. Factors found to be significantly associated with an increased risk of death from diarrhoea included the non-availability of piped water, the absence of a flush toilet, residence in a poorly built house and household overcrowding. When adjustment was made for confounding variables and the mutual confounding effect of the environmental variables on each other, the only association that remained statistically significant was that with the availability of piped water. The association with poor housing was almost significant (p = 0.052). Compared to those with water piped to their house, those without easy access to piped water were found to be 4.8 times more likely to suffer infant death from diarrhoea (95% confidence interval 1.7 to 13.8) and those with water piped to their plot but not to their house had a 1.5 times greater risk (95% confidence interval 0.8 to 3.0).
在巴西南部阿雷格里港和佩洛塔斯都会区开展的一项基于人群的病例对照研究中,对死于腹泻的婴儿与社区对照在若干社会和环境变量方面进行了比较。发现与腹泻死亡风险增加显著相关的因素包括无自来水供应、无冲水马桶、居住在建造简陋的房屋以及家庭过度拥挤。在对混杂变量以及环境变量之间的相互混杂效应进行调整后,唯一在统计学上仍具有显著意义的关联是与自来水供应情况的关联。与住房条件差的关联几乎具有显著性(p = 0.052)。与家中有自来水管道的人相比,那些难以获得自来水的人死于腹泻的婴儿的可能性高出4.8倍(95%置信区间为1.7至13.8),而地块有自来水管道但家中没有的人风险高出1.5倍(95%置信区间为0.8至3.0)。