Ijsselhof Rinske, Gauvreau Kimberlee, Nido Pedro Del, Nathan Meena
Department of Pediatric Cardiac Surgery, University Medical Center Utrecht, the Netherlands.
Department of Cardiology, Boston Children's Hospital, and Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
World J Pediatr Congenit Heart Surg. 2020 Mar;11(2):247-248. doi: 10.1177/2150135119893648.
Technical performance score (TPS) has been associated with both early and late outcomes across a wide range of congenital cardiac procedures. A previous study has shown that the presence of residual lesions before discharge, as measured by TPS, is accurately able to identify patients who required postdischarge reinterventions after complete atrioventricular septal defect (CAVSD) repair. The aim of this study is to determine which subcomponents of TPS best predict postdischarge reinterventions after CAVSD repair.
This was a single-center retrospective review of patients with CAVSD after repair between January 2000 and March 2016. We assigned TPS (class 1, no residua; class 2, minor residua; class 3, major residua or reintervention before discharge for residua) based on subcomponent scores from discharge echocardiograms. Outcome of interest was postdischarge reintervention.
Among 344 patients, median age was 3.2 months (interquartile range [IQR], 2.4-4.2). There were 34 (10%) postdischarge reinterventions. Median follow-up was 2.6 years (IQR, 0.09-7.9). Trisomy 21 and concomitant procedure were associated with postdischarge reinterventions. After adjusting for these factors, among the subcomponents, left atrioventricular valve stenosis and regurgitation, right atrioventricular valve regurgitation, residual ventricular septal defect, and abnormal conduction at discharge were significantly associated with postdischarge reinterventions.
We demonstrated the ability of TPS to predict postdischarge reinterventions in patients who underwent CAVSD repair. Residual left and right atrioventricular valve regurgitation and abnormal conduction at discharge were among the subcomponents strongly associated with postdischarge reinterventions. Thus, TPS may aid clinicians in identifying children at higher risk for reintervention.
技术性能评分(TPS)与多种先天性心脏手术的早期和晚期结果均相关。先前的一项研究表明,通过TPS测量,出院前残留病变的存在能够准确识别出在完全性房室间隔缺损(CAVSD)修复后需要出院后再次干预的患者。本研究的目的是确定TPS的哪些子成分最能预测CAVSD修复后出院后的再次干预。
这是一项对2000年1月至2016年3月期间接受修复的CAVSD患者的单中心回顾性研究。我们根据出院超声心动图的子成分评分来分配TPS(1级,无残留;2级,轻微残留;3级,严重残留或因残留而在出院前进行再次干预)。感兴趣的结局是出院后再次干预。
在344例患者中,中位年龄为3.2个月(四分位间距[IQR],2.4 - 4.2)。有34例(10%)出院后再次干预。中位随访时间为2.6年(IQR,0.09 - 7.9)。21三体综合征和同期手术与出院后再次干预相关。在对这些因素进行调整后,在子成分中,左房室瓣狭窄和反流、右房室瓣反流、残余室间隔缺损以及出院时的异常传导与出院后再次干预显著相关。
我们证明了TPS能够预测接受CAVSD修复患者的出院后再次干预。残留的左、右房室瓣反流以及出院时的异常传导是与出院后再次干预密切相关的子成分。因此,TPS可能有助于临床医生识别再次干预风险较高的儿童。