Division of Cardiology, Osaka Saiseikai Izuo Hospital, 3-4-5 Kitamura, Taisho-ku, Osaka, 551-0032, Japan.
Division of Nephrology, Osaka Saiseikai Izuo Hospital, 3-4-5 Kitamura, Taisho-ku, Osaka, 551-0032, Japan.
BMC Cardiovasc Disord. 2020 Feb 24;20(1):89. doi: 10.1186/s12872-020-01392-6.
Acute coronary syndrome (ACS) with high-grade atrioventricular block (HAVB) still has a poor mortality risk, even in the current percutaneous coronary intervention (PCI) era. However, early PCI for ACS with HAVB is associated with improved in-hospital survival and a 6-month survival similar to that of ACS without HAVB.
A 70-year-old man was admitted to our hospital for ACS with HAVB. ECG showed complete AV block, complete right bundle branch block (CRBBB), and left axis deviation. Cardiac enzymes were elevated. He underwent temporary pacemaker insertion and coronary angiography, which showed severe stenosis of the proximal right coronary artery (RCA), 99% stenosis of the distal RCA with Thrombolysis in Myocardial Infarction (TIMI) grade 2 flow, and total occlusion of the proximal left anterior descending artery (LAD). We performed primary PCI in both the RCA and LAD, which resulted in TIMI grade 3 flow in both. After PCI, the HAVB recovered to normal sinus rhythm with CRBBB; a normal QRS interval returned within three days. The patient was discharged from the hospital without complications.
In this case of ACS with HAVB, early intensive coronary artery reperfusion resulted in long-term patient survival. The blood supply to the AV node and bilateral bundle branches is complex. Multivessel ischemia may compromise both primary and collateral blood flows to the AV node and septum, resulting in severe conduction impairment. Clinicians performing PCI should be aware of this anatomy and physiology.
即使在当前经皮冠状动脉介入治疗(PCI)时代,急性冠状动脉综合征(ACS)伴高度房室传导阻滞(HAVB)仍然具有较高的死亡率。然而,ACS 伴 HAVB 的早期 PCI 与改善住院期间生存率和 6 个月生存率有关,与无 HAVB 的 ACS 相似。
一名 70 岁男性因 ACS 伴 HAVB 入院。心电图显示完全性房室传导阻滞、完全性右束支阻滞(CRBBB)和左轴偏。心肌酶升高。他接受了临时起搏器植入和冠状动脉造影术,显示右冠状动脉(RCA)近端严重狭窄,RCA 远端 99%狭窄,血流 TIMI 2 级,前降支(LAD)近端完全闭塞。我们对 RCA 和 LAD 进行了直接 PCI,均使血流达到 TIMI 3 级。PCI 后,HAVB 恢复为正常窦性心律伴 CRBBB;正常 QRS 间隔在三天内恢复。患者无并发症出院。
在本例 ACS 伴 HAVB 中,早期强化冠状动脉再灌注导致长期患者生存。房室结和双侧束支的血液供应复杂。多支血管缺血可能会影响房室结和间隔的主要和侧支血流,导致严重的传导障碍。进行 PCI 的临床医生应该了解这种解剖和生理学。