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新版 NRP 胎粪吸入综合征指南对足月婴儿结局的影响。

Impact of the Revised NRP Meconium Aspiration Guidelines on Term Infant Outcomes.

机构信息

Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois

Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

出版信息

Hosp Pediatr. 2020 Mar;10(3):295-299. doi: 10.1542/hpeds.2019-0155.

DOI:10.1542/hpeds.2019-0155
PMID:32094237
Abstract

OBJECTIVES

To evaluate the association of the Neonatal Resuscitation Program, Seventh Edition changes on term infants born with meconium-stained amniotic fluid (MSAF).

STUDY DESIGN

We evaluated the effect of no longer routinely intubating nonvigorous term infants born with MSAF in 14 322 infants seen by the resuscitation team from January 1, 2014 to June 30, 2017 in a large, urban, academic hospital.

RESULTS

Delivery room intubations of term infants with MSAF fell from 19% to 3% after the change in guidelines ( = <.0001). The rate of all other delivery room intubations also decreased by 3%. After the implementation of the Seventh Edition guidelines, 1-minute Apgar scores were significantly more likely to be >3 ( = .009) and significantly less likely to be <7 ( = .011). The need for continued respiratory support after the first day of life also decreased. Admission rates to the NICU, length of stay, and the need for respiratory support on admission were unchanged.

CONCLUSIONS

Implementation of the Neonatal Resuscitation Program, Seventh Edition recommendations against routine suctioning nonvigorous infants born with MSAF was temporally associated with an improvement in 1-minute Apgar scores and decreased the need for respiratory support after the first day of life. There was also a significant decrease in total intubations performed in the delivery room. This has long-term implications on intubation experience among frontline providers.

摘要

目的

评估第七版新生儿复苏计划(Neonatal Resuscitation Program,NRP)变化对胎粪污染羊水(meconium-stained amniotic fluid,MSAF)足月出生婴儿的影响。

研究设计

我们评估了在 2014 年 1 月 1 日至 2017 年 6 月 30 日期间,在一家大型城市学术医院的复苏团队中观察到的 14322 名胎粪污染羊水足月出生婴儿中,不再常规对非活力婴儿进行气管插管的影响。

结果

指南改变后,产房内对胎粪污染羊水足月出生婴儿的气管插管率从 19%降至 3%(<0.0001)。所有其他产房内气管插管率也降低了 3%。实施第七版指南后,1 分钟 Apgar 评分>3 的比例显著增加(=0.009),<7 的比例显著减少(=0.011)。出生后第一天需要持续呼吸支持的情况也减少了。新生儿重症监护病房(NICU)入院率、住院时间以及入院时的呼吸支持需求均无变化。

结论

实施第七版新生儿复苏计划建议,对胎粪污染羊水非活力足月出生婴儿不常规进行吸引,与 1 分钟 Apgar 评分的改善以及出生后第一天呼吸支持需求的减少有关。同时,产房内的总插管数量也显著减少。这对一线医护人员的插管经验具有长期影响。

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