Auguste Patrick, Leitinger Birgit, Liard Christelle, Rocher Virginie, Azema Laurent, Saltel Frederic, Santamaria David
INSERM, U1035, F-33076 Bordeaux, France
Université de Bordeaux, F-33076 Bordeaux, France.
J Cell Sci. 2020 Feb 24;133(4):jcs243824. doi: 10.1242/jcs.243824.
For the first time, a meeting dedicated to the tyrosine kinase receptors DDR1 and DDR2 took place in Bordeaux, a famous and historical city in the south of France. Over the course of 3 days, the meeting allowed 60 participants from 11 different countries to exchange ideas and their new findings about these unique collagen receptors, focusing on their role in various physiological and pathological conditions and addressing their mechanisms of regulation and signalling. The involvement of these receptors in different pathologies was also considered, with emphasis on cancer development and potential therapeutic applications. Here, we summarize the key elements of this meeting.
首次专门讨论酪氨酸激酶受体DDR1和DDR2的会议在法国南部一座著名的历史名城波尔多举行。在为期3天的会议期间,来自11个不同国家的60名与会者得以就这些独特的胶原蛋白受体交流想法和分享新发现,重点讨论了它们在各种生理和病理状况中的作用,以及调控和信号传导机制。会议还探讨了这些受体在不同病理状况中的作用,尤其关注癌症发展及潜在的治疗应用。在此,我们总结本次会议的要点。