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地塞米松植入术后并发症的外科治疗

Surgical Management of Complications after Dexamethasone Implant.

作者信息

Sborgia Giancarlo, Niro Alfredo, D'Oria Francesco, Galeone Alessandra, Sborgia Luigi, Boscia Francesco, Sborgia Alessandra, Alessio Giovanni

机构信息

Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari, Bari, Italy.

Eye Clinic, Hospital "S. G. MOSCATI, " ASL TA, Taranto, Italy.

出版信息

Case Rep Ophthalmol Med. 2020 Feb 10;2020:4837689. doi: 10.1155/2020/4837689. eCollection 2020.

DOI:10.1155/2020/4837689
PMID:32095301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7035535/
Abstract

PURPOSE

To report surgical management of ocular complications occurred after dexamethasone (DEX) implant (Ozurdex®) injection.

METHODS

Retrospective interventional case series.

RESULTS

Different surgical procedures including viscoexpression to manage the migration of the implant into the anterior chamber, "phaco-rolling" technique for the intralenticular injection, and vitrectomy with implant removal for an acute endophthalmitis were performed. Successful management of different complications after DEX implant by using individualized surgical approaches was observed.

CONCLUSIONS

Early and targeted surgical management is required in selected cases of ocular complications after DEX implant. The implant removal was needed to preserve ocular anatomy and function.

摘要

目的

报告地塞米松(DEX)植入物(Ozurdex®)注射后发生的眼部并发症的手术治疗。

方法

回顾性介入病例系列。

结果

实施了不同的手术操作,包括用于处理植入物向前房迁移的粘弹剂注入、用于晶状体囊内注射的“超声乳化滚动”技术,以及用于急性眼内炎的玻璃体切割联合植入物取出术。观察到通过采用个体化手术方法成功处理了DEX植入后的不同并发症。

结论

对于DEX植入后发生眼部并发症的特定病例,需要早期且有针对性的手术治疗。为了保留眼部结构和功能,需要取出植入物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9e/7035535/39663d3b0973/CRIOPM2020-4837689.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9e/7035535/9d3542e6c33d/CRIOPM2020-4837689.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9e/7035535/39663d3b0973/CRIOPM2020-4837689.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9e/7035535/9d3542e6c33d/CRIOPM2020-4837689.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9e/7035535/39663d3b0973/CRIOPM2020-4837689.002.jpg

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Retina. 2020 May;40(5):825-832. doi: 10.1097/IAE.0000000000002475.
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Complications of Intravitreous Injections in Patients with Diabetes.糖尿病患者玻璃体内注射的并发症
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The clinical outcomes of surgical management of anterior chamber migration of a dexamethasone implant (Ozurdex®).
玻璃体切除术后细菌眼内炎患眼持续性囊样黄斑水肿应用玻璃体内注射地塞米松植入物的中期安全性和有效性。
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Pharmacokinetics of Pullulan-Dexamethasone Conjugates in Retinal Drug Delivery.普鲁兰多糖-地塞米松缀合物在视网膜药物递送中的药代动力学
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地塞米松植入物(Ozurdex®)前房移位的手术治疗临床结果
Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1819-1825. doi: 10.1007/s00417-017-3705-y. Epub 2017 Jun 10.
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No-Touch Removal of Anterior Segment-Migrated Dexamethasone Implant.前段迁移地塞米松植入物的非接触式取出
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The Association between Intravitreal Steroids and Post-Injection Endophthalmitis Rates.玻璃体内注射类固醇与注射后眼内炎发生率之间的关联。
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