Didace Massamba Miabaou, Ida Lenga Loumingou, Irène Ondima, Félix Peko Jean
Department of Digestive Surgery, Brazzaville Teaching University Hospital, Brazzaville, Congo.
Department of Dermatology, Brazzaville Teaching University Hospital, Brazzaville, Congo.
Case Rep Surg. 2020 Feb 10;2020:7840963. doi: 10.1155/2020/7840963. eCollection 2020.
Tuberculosis is an endemic emergency that is prevalent in developing countries, particularly in sub-Saharan Black Africa, including Congo-Brazzaville. In addition to the pulmonary, ganglionic, and bone forms, there are other poorly documented locations. In the Congo, among these is cutaneous tuberculosis which is exceptional. A 9-year-old boy and two adult patients had persistent lesions of the left hip and thigh wounds, chest wall, and hypogastric wound with no healing for more than four months, respectively. Among these patients, one case of tuberculous contact was noted. Histopathological examination revealed a Koester follicle, suggesting a tuberculous skin fistula. A fistulectomy was performed, coupled with a quadruple antituberculous therapy combining rifampicin, isoniazid, ethambutol, and pyrazinamide for two months, relayed by a dual therapy consisting of isoniazid and ethambutol for 6 to 8 months. The evolution was favorable in all cases with healing of the lesions after 3 to 6 weeks. The existence of inexhaustible fistulas and the absence of scarring of a wound should make one suspect, among other things, cutaneous tuberculosis. The product of fistulectomy makes it possible to establish the histological diagnosis of cutaneous tuberculosis.
结核病是一种在发展中国家流行的地方性急症,特别是在撒哈拉以南的非洲黑人地区,包括刚果布拉柴维尔。除了肺部、淋巴结和骨骼形式外,还有其他记录较少的发病部位。在刚果,其中包括罕见的皮肤结核。一名9岁男孩和两名成年患者分别有左髋部和大腿伤口、胸壁以及下腹部伤口的持续性病变,超过四个月未愈合。在这些患者中,发现了一例结核接触病例。组织病理学检查发现了科斯特氏滤泡,提示为结核性皮肤瘘管。进行了瘘管切除术,并联合使用利福平、异烟肼、乙胺丁醇和吡嗪酰胺进行了两个月的四联抗结核治疗,之后由异烟肼和乙胺丁醇组成的二联疗法持续6至8个月。所有病例的病情发展都很顺利,病变在3至6周后愈合。存在经久不愈的瘘管且伤口无瘢痕形成,除其他情况外,应使人怀疑为皮肤结核。瘘管切除产物有助于建立皮肤结核的组织学诊断。