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临床微生物学实验室的有效利用。

Effective use of the clinical microbiology laboratory.

作者信息

Washington J A

机构信息

Department of Microbiology, Cleveland Clinic Foundation, Ohio 44195.

出版信息

J Antimicrob Chemother. 1988 Jul;22 Suppl A:101-12. doi: 10.1093/jac/22.supplement_a.101.

Abstract

The clinician's expectations of the clinical microbiology laboratory, while valid, have not always been fulfilled. Major limitations in the accurate identification of an aetiological agent are imposed by cost considerations and poor communication between clinician and laboratory personnel. Other difficulties arise in the entire process of making use of a clinical microbiology laboratory, ranging from specimen collection to interpretation of results. These problems can be partially overcome by the use of guidelines for specimen collection which are designed to provide a sufficient amount of material and number of specimens for complete examination. Additional assistance to the clinician may be rendered by the current trends in clinical microbiology practice to limit the processing of inappropriate specimens and to develop rapid, economical procedures for the detection of pathogenic microorganisms. The clinician should not routinely request antibiotic susceptibility testing but rather base the decision to test on specimen source, type of organism isolated, whether the organisms was isolated in pure or mixed culture, and how predictable the susceptibility of the organism is to the drug of choice.

摘要

临床医生对临床微生物实验室的期望虽合理,但并非总能实现。成本考量以及临床医生与实验室人员之间沟通不畅,给准确鉴定病原体带来了重大限制。在利用临床微生物实验室的整个过程中,从标本采集到结果解读,还会出现其他困难。通过使用标本采集指南,这些问题可得到部分解决,该指南旨在提供足够数量的材料和标本用于全面检查。临床微生物学实践的当前趋势,即限制对不适当标本的处理,并开发快速、经济的致病微生物检测程序,可为临床医生提供更多帮助。临床医生不应常规要求进行抗生素敏感性测试,而应根据标本来源、分离出的生物体类型、生物体是在纯培养还是混合培养中分离出来的,以及该生物体对首选药物的敏感性可预测程度来决定是否进行测试。

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