Konstantinovic Neda, Guegan Hélène, Stäjner Tijana, Belaz Sorya, Robert-Gangneux Florence
National Reference Laboratory for Toxoplasmosis, Institute for Medical Research, University of Belgrade, 11129 Belgrade, Serbia.
Univ Rennes, CHU Rennes, Inserm, EHESP, Irset - UMR_S 1085, F-35000 Rennes, France.
Food Waterborne Parasitol. 2019 Apr 1;15:e00036. doi: 10.1016/j.fawpar.2019.e00036. eCollection 2019 Jun.
Toxoplasmosis is a worldwide parasitic disease infecting about one third of humans, with possible severe outcomes in neonates and immunocompromised patients. Despite continuous and successful efforts to improve diagnosis, therapeutic schemes have barely evolved since many years. This article aims at reviewing the main clinical trials and current treatment practices, and at addressing future perspectives in the light of ongoing researches.
弓形虫病是一种全球性的寄生虫病，感染了约三分之一的人类，在新生儿和免疫功能低下的患者中可能会导致严重后果。尽管在改进诊断方面持续做出了成功努力，但多年来治疗方案几乎没有进展。本文旨在综述主要的临床试验和当前的治疗实践，并根据正在进行的研究探讨未来的前景。
