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早发性脊柱侧弯后路脊柱融合术后近端交界性后凸畸形

Proximal junction kyphosis after posterior spinal fusion for early-onset scoliosis.

作者信息

Piantoni Lucas, Remondino Rodrigo G, Tello Carlos A, Wilson Ida A Francheri, Galaretto Eduardo, Noel Mariano A

机构信息

Servicio de Patología Espinal, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881, C1245AAM, Buenos Aires, Argentina.

出版信息

Spine Deform. 2020 Apr;8(2):311-316. doi: 10.1007/s43390-020-00029-0. Epub 2020 Feb 24.

Abstract

STUDY DESIGN

Retrospective study.

OBJECTIVE

The aim of this study was to assess the presence of proximal junctional kyphosis (PJK) in our population of children with early-onset scoliosis (EOS) and to identify the predisposing factors for the development of PJK in the postoperative period after posterior spinal fusion (PSF). Few studies have been conducted to evaluate the incidence of proximal junction kyphosis (PJK) in children after early-onset scoliosis (EOS) after posterior spinal fusion (PSF).

MATERIALS AND METHODS

Overall, 114 pediatric patients aged < 10 years who underwent surgery for scoliosis or kyphoscoliosis at a single center between 2013 and 2015 were evaluated. Forty-five patients submitted to PSF of five or more levels met the inclusion criteria. The sample included 12 female and 10 male patients. Mean age at surgery was 7 years and 8 months.

RESULTS

PJK was observed in 22 patients (48.9%). Overall, the mean proximal junctional angle at 12 and 36 months was 17.1° and 22°, respectively. The uppermost instrumented vertebra (UIV) with the highest PJK rate was T6-T7. The lowest instrumented vertebra (LIV) with the highest PJK rate was L2. Etiology was idiopathic in 4, neuromuscular in 11, congenital in 14, and syndromic in 16. According to underlying disorder, prevalence of PJK was 78% in those with a congenital, 50% in those with a syndromic, 12% in those with idiopathic, and 9% in those with a neuromuscular EOS. Surgical revision rate was 4% (one patient). Mean postoperative follow-up was of 3 years and 4 months (range 3-4 years and 1 month).

CONCLUSION

Congenital and syndromic etiology, but not age at PJK onset or sex of the patient, significantly affected the incidence rate of PJK. The UIV with the highest PJK rate was T6-T7 and the LIV with the highest PJK rate was L2. The patients had a low surgical revision rate.

LEVEL OF EVIDENCE

Level IV.

摘要

研究设计

回顾性研究。

目的

本研究旨在评估我们的早发性脊柱侧凸(EOS)儿童群体中近端交界性后凸(PJK)的存在情况,并确定后路脊柱融合术(PSF)术后PJK发生的易感因素。很少有研究评估早发性脊柱侧凸(EOS)患儿后路脊柱融合术(PSF)后近端交界性后凸(PJK)的发生率。

材料与方法

共评估了2013年至2015年间在单一中心接受脊柱侧凸或脊柱后凸畸形手术的114例年龄小于10岁的儿科患者。45例行5个或更多节段PSF的患者符合纳入标准。样本包括12例女性和10例男性患者。手术时的平均年龄为7岁8个月。

结果

22例患者(48.9%)观察到PJK。总体而言,12个月和36个月时的平均近端交界角分别为17.1°和22°。PJK发生率最高的最上位固定椎体(UIV)为T6-T7。PJK发生率最高的最下位固定椎体(LIV)为L2。病因方面,特发性4例,神经肌肉性11例,先天性14例及综合征性16例。根据潜在疾病,先天性EOS患者中PJK的患病率为78%,综合征性患者中为50%,特发性患者中为12%,神经肌肉性EOS患者中为9%。手术翻修率为4%(1例患者)。术后平均随访时间为3年4个月(范围3至4年1个月)。

结论

先天性和综合征性病因,而非PJK发病年龄或患者性别,显著影响PJK的发生率。PJK发生率最高的UIV为T6-T7,LIV为L2。患者的手术翻修率较低。

证据水平

IV级。

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