Cao Lirong, Wang Yizheng, Zhao Linsheng, Hu Xiaoli, Cai Chunquan
The Affiliated Hospital of Hebei University, Baoding City, Hebei Province.
The People's Hospital of Jizhou District, Tianjin.
Clin Dysmorphol. 2020 Apr;29(2):81-85. doi: 10.1097/MCD.0000000000000318.
Congenital dermoid inclusion cyst (CDIC) over the anterior fontanel is a rare and benign tumor. This study reports nine Chinese cases (three females and six males) with CDIC over the anterior fontanel. The clinical manifestations and imaging were analyzed retrospectively. Surgical resection was undertaken in all cases. The diagnosis of CDIC over the anterior fontanel was confirmed by histological examination. The cysts were all noticed soon after birth and enlarged gradually. They were soft, nontender with a sessile base without inflammatory signs and breaking. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed soft tissue mass over the anterior fontanel without intracranial extensions. The histopathological examination displayed stratified squamous epithelium with skin appendages. There were no complications or recurrence after operation during a follow-up for one year. CDIC over the anterior fontanel is a benign tumor. Imaging is recommended preoperatively to aid differential diagnosis. The main management is total excision with good prognosis.
前囟先天性皮样包涵囊肿（CDIC）是一种罕见的良性肿瘤。本研究报告了9例中国前囟CDIC患者（3例女性，6例男性）。对其临床表现和影像学表现进行回顾性分析。所有病例均行手术切除。经组织学检查确诊为前囟CDIC。囊肿均在出生后不久被发现，并逐渐增大。囊肿质地柔软，无压痛，基底部无蒂，无炎症体征及破溃。计算机断层扫描（CT）和磁共振成像（MRI）显示前囟处软组织肿块，无颅内延伸。组织病理学检查显示为伴有皮肤附属器的复层鳞状上皮。随访1年期间，术后无并发症及复发。前囟CDIC是一种良性肿瘤。建议术前进行影像学检查以辅助鉴别诊断。主要治疗方法是完整切除，预后良好。
