Center for Reproductive Biology, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Center for Reproductive Biology, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Dev Cell. 2020 Feb 24;52(4):397-398. doi: 10.1016/j.devcel.2020.02.002.
The capacity to undergo meiosis defines vertebrate germ cells, yet mechanisms driving initiation of this specialized process are largely undefined. In this issue of Developmental Cell,Ishiguro et al. (2020) identified the transcription factor MEIOSIN as a gatekeeper of meiotic initiation in both male and female germ cells.
能够进行减数分裂定义了脊椎动物的生殖细胞，但启动这个特殊过程的机制在很大程度上还不清楚。在本期《发育细胞》中，Ishiguro 等人（2020）鉴定出转录因子 MEIOSIN 是雄性和雌性生殖细胞中减数分裂起始的守门员。
