在以色列，[病原体名称]的胎盘传播并非马驹流产和感染的常见原因。 （注：原文中“Is Not a Common Cause of Abortions and Infection of Foals in Israel.”缺少具体病原体相关内容，翻译时补充了[病原体名称]使句子完整通顺）
Transplacental Transmission of Is Not a Common Cause of Abortions and Infection of Foals in Israel.
作者信息
Tirosh-Levy Sharon, Gottlieb Yuval, Mimoun Lea, Mazuz Monica L, Steinman Amir
机构信息
Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, 7610001 Rehovot, Israel.
Division of Parasitology, Kimron Veterinary Institute, 50250 Bet Dagan, Israel.
出版信息
Animals (Basel). 2020 Feb 21;10(2):341. doi: 10.3390/ani10020341.
Although the main route of transmission of is through tick feeding, transplacental transmission is also possible and may lead to abortion, or to the birth of a sick or carrier foal. The aim of this study was to evaluate the role of as a cause of abortions in Israel and the risk of foals being infected at a young age. Eight aborting mares were serologically evaluated for exposure to via the immunofluorescence antibody test (IFAT) and their aborted fetuses were evaluated using PCR and qPCR. In addition, five mares and their foals (aged 4-6 months) from a highly endemic farm were tested for infection using IFAT, PCR and qPCR. Five of the eight aborting mares were seropositive for ; however, none of the aborted fetuses was infected. All five mares from the endemic farm were subclinically infected with . Of their five foals, one was infected, with relatively high parasitemia and different parasite genotype than its dam's, suggesting another source of infection. The results of this study suggest that transplacental transmission of is not common and does not appear to be a prominent cause of abortion in chronically infected mares.
虽然[病原体名称]的主要传播途径是通过蜱虫叮咬，但经胎盘传播也是可能的，并且可能导致流产，或生出患病或携带病原体的马驹。本研究的目的是评估[病原体名称]在以色列作为流产原因的作用以及马驹在幼年时被感染的风险。对8匹流产母马通过免疫荧光抗体试验（IFAT）进行血清学评估以检测其是否接触过[病原体名称]，并使用PCR和qPCR对其流产胎儿进行评估。此外，对来自一个高度流行农场的5匹母马及其4至6个月大的马驹使用IFAT、PCR和qPCR检测[病原体名称]感染情况。8匹流产母马中有5匹[病原体名称]血清学检测呈阳性；然而，流产胎儿均未被感染。来自流行农场的5匹母马均受到[病原体名称]亚临床感染。在它们的5匹马驹中，有1匹被感染，其寄生虫血症相对较高，且寄生虫基因型与其母马不同，这表明存在另一个感染源。本研究结果表明，[病原体名称]的经胎盘传播并不常见，似乎也不是慢性感染母马流产的主要原因。
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