Eichler I, Frisch H, Eichler H G, Soukop W
Department of Pediatrics, University Hospital, Vienna, Austria.
J Endocrinol Invest. 1988 Jun;11(6):409-11. doi: 10.1007/BF03349069.
In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resulted in biochemical (somatomedin increase) and clinical (catch up growth) response.
一名12岁男孩在严重头部创伤后出现生长停滞。垂体内分泌功能评估显示孤立性生长激素（GH）缺乏。对生长激素释放因子缺乏GH反应表明，责任病变很可能定位于垂体。GH替代治疗产生了生化反应（生长介素增加）和临床反应（追赶生长）。
