Hoang N M, Smadja A, Orcel L
Laboratoire d'Anatomie Pathologique, C.H.U., Amiens.
J Gynecol Obstet Biol Reprod (Paris). 1988;17(4):479-84.
The purpose of this study was to evaluate comparatively the morphology of germinal epithelium and of peritoneal mesothelial cells in women with and without endometriotic foci. In women without enometriotic foci, transmission electron microscopy revealed that plasma membranes of both cell types can form villous process, and that tonofilaments can be found in the cytoplasm; the microfibrils are well defined and may be arranged in perinuclear location or closely packed on the surface. Desmosomes are occasionally found in both cell types. In endometriotic foci, located either in the peritoneum or in the ovary, invaginations of the mesothelium into the underlying stroma are frequently observed, contiguous to well defined endometriotic tubules, or glandlike crypts. These structures are lined by a layer of cuboidal or high columnar cells. The cell membranes are well defined and run parallel to one another; small widening of the intercellular spaces is occasionally associated with a desmosome in the apical portion of the cell. These features may reflect Mullerian induction.
本研究的目的是比较评估有和没有子宫内膜异位病灶的女性生发上皮和腹膜间皮细胞的形态。在没有子宫内膜异位病灶的女性中，透射电子显微镜显示，两种细胞类型的质膜均可形成绒毛状突起，并且在细胞质中可发现张力丝；微原纤维清晰可辨，可能排列在核周位置或紧密堆积在表面。两种细胞类型中偶尔可见桥粒。在位于腹膜或卵巢的子宫内膜异位病灶中，经常观察到间皮向下方基质内陷，与明确的子宫内膜异位小管或腺样隐窝相邻。这些结构由一层立方或高柱状细胞内衬。细胞膜清晰可辨且彼此平行；细胞间隙偶尔会有小的增宽，并在细胞顶端部分伴有一个桥粒。这些特征可能反映了苗勒管诱导。
