Clinic of Vascular Surgery, Krankenhaus Barmherzige Brüder Regensburg, Pruefeningerstrasse 81, Regensburg, 93049, Germany.
Clinic of Vascular Surgery, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Germany.
Scand J Surg. 2021 Sep;110(3):400-406. doi: 10.1177/1457496920907733. Epub 2020 Feb 25.
Arteriosclerotic disease of the common femoral artery can be treated by surgical or endovascular intervention. Elderly patients are said to have a worse outcome if treated by surgical means; however, data to support this theory are missing.
Retrospective analysis of all patients who underwent common femoral artery endarterectomy between March 2007 and July 2018 in our clinic. Group 1 included all patients <80 years and Group 2 included all patients ⩾80 years. Endpoints were patency rates, limb salvage, and overall survival.
During this time period, 977 common femoral artery endarterectomies were performed. Indication was claudication in 61.5% and critical limb ischemia in 38.5%. Group 1 included 805 cases (82.4%) and Group 2 included 172 cases (17.6%). Thirty-day mortality was 2.7% (Group 1 = 1.6% versus Group 2 = 7.6%; < 0.001) and 30-day major amputation was 1.1% (Group 1 = 0.7% versus Group 2 = 2.9%; = .043). Primary patency and secondary patency were 84.2% and 96.8%, respectively, after 7 years. Limb salvage (93.7%, Group 1 = 94.1% versus Group 2 = 91.8%; = .088) and overall survival (52.0%, Group 1 = 59.1% versus Group 2 = 15.7%; = .006) were significantly different after the same time period. Multivariable analysis showed female gender to be a risk factor for loss of primary patency. Age ⩾ 80 years and ulcer or gangrene were risk factors for death. Statin use was beneficial to survival.
Common femoral artery endarterectomy is a safe procedure with excellent long-term results. Octogenarians have an increased risk for perioperative mortality and major amputation.
股总动脉粥样硬化性疾病可通过手术或血管内介入治疗。有人说,老年患者如果采用手术治疗,其预后较差,但缺乏支持这一理论的数据。
回顾性分析 2007 年 3 月至 2018 年 7 月期间在我院行股总动脉内膜切除术的所有患者。第 1 组包括所有年龄<80 岁的患者,第 2 组包括所有年龄 ⩾80 岁的患者。终点为通畅率、肢体挽救率和总生存率。
在此期间,共行 977 例股总动脉内膜切除术。适应证为跛行 61.5%,严重肢体缺血 38.5%。第 1 组包括 805 例(82.4%),第 2 组包括 172 例(17.6%)。30 天死亡率为 2.7%(第 1 组 1.6%,第 2 组 7.6%; ⁇ <0.001),30 天主要截肢率为 1.1%(第 1 组 0.7%,第 2 组 2.9%; ⁇ =0.043)。7 年后,原发性通畅率和继发性通畅率分别为 84.2%和 96.8%。同样在 7 年后,肢体挽救率(93.7%,第 1 组 94.1%,第 2 组 91.8%; ⁇ =0.088)和总生存率(52.0%,第 1 组 59.1%,第 2 组 15.7%; ⁇ =0.006)差异有统计学意义。多变量分析显示,女性是原发性通畅率丧失的危险因素。年龄 ⁇ ⁇ 80 岁和溃疡或坏疽是死亡的危险因素。他汀类药物的使用有利于生存。
股总动脉内膜切除术是一种安全的手术,具有良好的长期效果。80 岁以上的老年人围手术期死亡率和主要截肢率增加。