Pomerri F, Pittarello F, Muzzio P C
Radiology Institute, Padua University, Italy.
Int J Pancreatol. 1988;3 Suppl 1:S131-6.
Fifty-three patients underwent endoscopic retrograde cholangiopancreatography (ERCP). Thirty-eight patients had pancreatic disease, diagnosed on the basis of surgical and/or instrumental-clinical findings, and consisted of 17 cases of carcinoma (group A), 10 cases of chronic pancreatitis with benign stenosis of the pancreatic duct (group B), and 11 cases of chronic pancreatitis without stenosis (group C). Linear discriminant analysis was employed to evaluate differential diagnosis data relative to secondary pancreatic ducts. With this method, 16/17 patients (94%) were correctly assigned to group A (high sensitivity), 7/8 patients (88%) to group B, and 7/10 patients (70%) to group C. A readily found radiological sign, such as abrupt and/or irregular stenosis of the pancreatic duct enables the correct diagnosis of carcinoma, but while this criterion is highly specific, it is poorly sensitive. If a clearly neoplastic stenosis of the main duct is not present, an analysis of the secondary ducts is determinant.
53例患者接受了内镜逆行胰胆管造影（ERCP）检查。38例患者患有胰腺疾病，根据手术和/或器械临床检查结果确诊，其中包括17例胰腺癌患者（A组）、10例伴有胰管良性狭窄的慢性胰腺炎患者（B组）以及11例无狭窄的慢性胰腺炎患者（C组）。采用线性判别分析来评估与二级胰管相关的鉴别诊断数据。通过这种方法，17例A组患者中有16例（94%）被正确归类（敏感性高），8例B组患者中有7例（88%），10例C组患者中有7例（70%）。胰管突然和/或不规则狭窄等易于发现的放射学征象能够正确诊断胰腺癌，但该标准虽然特异性高，但敏感性较差。如果不存在主胰管明显的肿瘤性狭窄，对二级胰管的分析则起决定性作用。
