术中眼用润滑剂对玻璃体视网膜手术中角膜清创率的影响
Impact of Intraoperative Ocular Lubricants on Corneal Debridement Rate During Vitreoretinal Surgery.
作者信息
Mathison Michael L, Li Albert S, Bao Yicheng K, Huang Andrew Jw, Rajagopal Rithwick
机构信息
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Department of Medicine, University of Missouri - Kansas City School of Medicine, Kansas City, MO 64112, USA.
出版信息
Clin Ophthalmol. 2020 Feb 4;14:347-352. doi: 10.2147/OPTH.S234149. eCollection 2020.
PURPOSE
To compare surgical parameters among patients receiving Viscoat (sodium chondroitin sulfate 4%-sodium hyaluronate 3%) or Goniosol (hydroxypropyl methylcellulose 2.5%) as topical lubricants for retinal surgery.
METHODS
This was a retrospective analysis of patients undergoing retinal surgery between March 2013 and March 2018 using Goniosol or Viscoat as adjuvants. Primary outcome measures were rate of corneal debridement and operative time between groups, compared using and -tests, respectively.
RESULTS
Compared to Viscoat (n=319), the Goniosol group (n=210) had more frequent intraoperative corneal debridement (21.4% vs 0, <0.05) and longer surgical times (98 vs 78 minutes, <0.05). Patients in the Viscoat group had higher rates of complex procedures (34.8% vs 26.7%, <0.05), but were younger (50.7 vs 55.0 years, <0.05) and more likely to be phakic (83.4% vs 70.5%, <0.05).
CONCLUSION
These findings suggest potential advantages of using Viscoat over Goniosol for corneal lubrication to aid visualization during vitreoretinal surgery.
目的
比较接受维施克（硫酸软骨素钠4%-透明质酸钠3%）或眼用粘弹剂（羟丙基甲基纤维素2.5%）作为视网膜手术局部润滑剂的患者的手术参数。
方法
这是一项对2013年3月至2018年3月期间接受视网膜手术并使用眼用粘弹剂或维施克作为佐剂的患者的回顾性分析。主要观察指标是两组之间的角膜清创率和手术时间，分别使用卡方检验和t检验进行比较。
结果
与维施克组（n = 319）相比，眼用粘弹剂组（n = 210）术中角膜清创更频繁（21.4% 对0，P<0.05），手术时间更长（98对78分钟，P<0.05）。维施克组患者复杂手术的发生率更高（34.8% 对26.7%，P<0.05），但年龄更小（50.7对55.0岁，P<0.05），晶状体眼的可能性更大（83.4% 对70.5%，P<0.05）。
结论
这些发现表明，在玻璃体视网膜手术中，使用维施克进行角膜润滑以辅助可视化可能比眼用粘弹剂具有潜在优势。
Zotero 插件