获得性因子 XIII 缺乏症引发反复致命性出血：一例病例描述
Acquired Factor XIII Deficiency Inducing Recurrent and Fatal Bleeding, Description of a Case.
作者信息
Di Micco Pierpaolo, Gussoni Gualberto, Pieralli Filippo, Campanini Mauro, Dentali Francesco, Fontanella Andrea
机构信息
Department of Internal Medicine and Emergency Room, Fatebenefratelli Hospital of Naples, Naples, Italy.
Centro Studi FADOI, Milan, Italy.
出版信息
J Blood Med. 2020 Jan 30;11:43-45. doi: 10.2147/JBM.S232115. eCollection 2020.
Abstract
Factor XIII deficiency may be inherited or acquired. Inherited deficiency is associated with signs and symptoms of minor bleeding from a young age, and possible major bleeding complications, in particular during pregnancy. On the other hand, acquired factor XIII deficiency is usually associated with severe symptoms of major bleeding, in particular during surgery. In this paper, we report an interesting case of recurrent major bleeding with subsequent fatal bleeding in an adult man diagnosed with acquired factor XIII deficiency.
摘要
凝血因子 XIII 缺乏症可能是遗传性的或后天获得性的。遗传性缺乏症与自幼出现的轻微出血症状以及可能的严重出血并发症有关，尤其是在怀孕期间。另一方面，后天获得性凝血因子 XIII 缺乏症通常与严重的大出血症状有关，特别是在手术期间。在本文中，我们报告了一例有趣的病例，一名成年男性被诊断为后天获得性凝血因子 XIII 缺乏症，反复出现严重出血并最终因出血死亡。
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