Fekrazad Reza, Fazilat Farzad, Kalhori Katayoun Am, Hakimiha Neda, Amirmoini Mehrdad, Nikhalat Jahromi Maryam
Radiation Sciences Research Center, Laser Research Center in Medical Sciences, AJA University of Medical Sciences, Tehran, Iran.
International Network for Photo Medicine and Photo Dynamic Therapy (INPMPDT), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
J Lasers Med Sci. 2020 Winter;11(1):104-107. doi: 10.15171/jlms.2020.17. Epub 2020 Jan 18.
Juvenile hyaline fibromatosis (JHF) is an unknown hereditary disorder with variable penetrance. The characterizations of this disease consist of different signs and symptoms such as multiple tumorous (tumor-like) muco-cutaneous proliferation, gingival hypertrophy, perianal lesions, articular contractures, and osteolytic lesions. A 3-year-old girl with numerous painless nodular masses on her gingival, ear and anal areas is presented in this case report. Based on characteristic histological features, the diagnosis of JHF was made. The patient underwent surgery following general anesthesia and the above areas were surgically operated with appropriate laser parameters, and the patient was able to eat and wash away after a day and was discharged with an antibiotic prescription after one day in the hospital and returned to normal after a week. The recurrence occurred in other areas a year later, especially in the cheek, the ears and the anal area. Therefore, this rare case is presented with recurrence.
青少年透明纤维瘤病(JHF)是一种具有可变外显率的不明遗传性疾病。该疾病的特征包括多种体征和症状,如多发性肿瘤样(肿瘤样)黏膜皮肤增殖、牙龈肥大、肛周病变、关节挛缩和溶骨性病变。本病例报告介绍了一名3岁女孩,其牙龈、耳部和肛门区域有许多无痛性结节状肿块。根据特征性组织学特征,诊断为JHF。患者在全身麻醉下接受手术,上述区域采用适当的激光参数进行手术操作,术后一天患者能够进食和洗漱,住院一天后开具抗生素处方出院,一周后恢复正常。一年后,其他部位出现复发,尤其是脸颊、耳部和肛门区域。因此,本罕见病例出现了复发情况。